Literature DB >> 23017154

Effective pharmacological treatment of painful diabetic neuropathy by nurse practitioners: results of an algorithm-based experience.

Margot Geerts1, Sabine A N T Landewé-Cleuren, Marleen Kars, Hubertus J M Vrijhoef, Nicolaas C Schaper.   

Abstract

OBJECTIVE: To improve the care of patients with painful diabetic polyneuropathy (PDP) by a specialized outpatient clinic for individuals referred by general practitioners and to determine the effects on pain, quality of life, and patient satisfaction.
MATERIAL AND METHODS: One hundred twenty-one patients were prospectively enrolled. At baseline and after 12 months at end of treatment, patients filled in a set of validated questionnaires on severity and interference of pain, quality of life, anxiety and depression, and patient satisfaction with the service offered.
SETTING: The outpatient clinic is part of a regional chronic care management program, which includes both hospital-based endocrinologists and general practitioners.
RESULTS: Twenty-eight patients (27%) did not need any further treatment after one visit to the outpatient clinic. As initial drug, pregabalin was the most commonly prescribed drug (65%); amitriptyline was prescribed in only 30% due to its contraindications. Improvements were found in all pain scores (P < 0.05). Pain interference was improved in sleep (P < 0.01), general activity, and mood (P < 0.05). More than half of the patients (65%) were satisfied with the treatment and wished no further medication changes; 52% had a treatment success defined as pain relief ≥ 30%. Medication was stopped due to inefficacy in 9% of patients and changed due to adverse effects in 20% of the patients.
CONCLUSIONS: A specialized outpatient clinic for patients with PDP is an effective health care service. Using diagnostic instruments and a defined treatment algorithm, significant pain reduction was achieved in the majority of patients in a relative short period of time. Wiley Periodicals, Inc.

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Year:  2012        PMID: 23017154     DOI: 10.1111/j.1526-4637.2012.01469.x

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  3 in total

Review 1.  Pathways in the diagnosis and management of diabetic polyneuropathy.

Authors:  Michelle Kaku; Aaron Vinik; David M Simpson
Journal:  Curr Diab Rep       Date:  2015-06       Impact factor: 4.810

2.  Effectiveness of Exposure in Vivo for Patients with Painful Diabetic Neuropathy: a Pilot Study of Effects on Physical Activity and Quality of Life.

Authors:  Charlotte C M van Laake-Geelen; Rob J E M Smeets; Marielle E J B Goossens; Jeanine A Verbunt
Journal:  J Rehabil Med Clin Commun       Date:  2021-02-10

3.  Biopsychosocial Rehabilitation Treatment "Exposure In Vivo" for Patients with Painful Diabetic Neuropathy: Development of a Treatment Protocol.

Authors:  Charlotte C M Van Laake-Geelen; Rob J E M Smeets; Thijs Van Meulenbroek; Marlies Den Hollander; Marielle E J B Goossens; Jeanine A Verbunt
Journal:  J Rehabil Med Clin Commun       Date:  2019-06-15
  3 in total

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