Literature DB >> 23015196

Wnt signaling in vertebrate neural development and function.

Kimberly A Mulligan1, Benjamin N R Cheyette.   

Abstract

Members of the Wnt family of secreted signaling proteins influence many aspects of neural development and function. Wnts are required from neural induction and axis formation to axon guidance and synapse development, and even help modulate synapse activity. Wnt proteins activate a variety of downstream signaling pathways and can induce a similar variety of cellular responses, including gene transcription changes and cytoskeletal rearrangements. This review provides an introduction to Wnt signaling pathways and discusses current research on their roles in vertebrate neural development and function.

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Mesh：

Year:  2012        PMID： 23015196      PMCID： PMC3518582          DOI： 10.1007/s11481-012-9404-x

Source DB:  PubMed          Journal:  J Neuroimmune Pharmacol        ISSN： 1557-1890            Impact factor:   4.147


  133 in total

1.  Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm.

Authors:  A G Bang; N Papalopulu; M D Goulding; C Kintner
Journal:  Dev Biol       Date:  1999-08-15       Impact factor: 3.582

2.  Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus.

Authors:  L L McGrew; S Hoppler; R T Moon
Journal:  Mech Dev       Date:  1997-12       Impact factor: 1.882

3.  WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum.

Authors:  Yanxin Pei; Sonja N Brun; Shirley L Markant; William Lento; Paul Gibson; Makoto M Taketo; Marco Giovannini; Richard J Gilbertson; Robert J Wechsler-Reya
Journal:  Development       Date:  2012-03-29       Impact factor: 6.868

4.  Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance.

Authors:  Beth Shafer; Keisuke Onishi; Charles Lo; Gulsen Colakoglu; Yimin Zou
Journal:  Dev Cell       Date:  2011-02-15       Impact factor: 12.270

5.  Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development.

Authors:  K R Thomas; M R Capecchi
Journal:  Nature       Date:  1990-08-30       Impact factor: 49.962

6.  Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling.

Authors:  Corinne Houart; Luca Caneparo; Carl Heisenberg; K Barth; Masaya Take-Uchi; Stephen Wilson
Journal:  Neuron       Date:  2002-07-18       Impact factor: 17.173

7.  Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.

Authors:  Chikara Kokubu; Ulrich Heinzmann; Tomoko Kokubu; Norio Sakai; Takuo Kubota; Masanobu Kawai; Matthias B Wahl; Juan Galceran; Rudolf Grosschedl; Keiichi Ozono; Kenji Imai
Journal:  Development       Date:  2004-10-06       Impact factor: 6.868

8.  Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors.

Authors:  Carolyn N Wrobel; Christopher A Mutch; Sruthi Swaminathan; Makoto M Taketo; Anjen Chenn
Journal:  Dev Biol       Date:  2007-07-24       Impact factor: 3.582

9.  Wnt and Bmp signalling cooperatively regulate graded Emx2 expression in the dorsal telencephalon.

Authors:  Thomas Theil; Songül Aydin; Silke Koch; Lars Grotewold; Ulrich Rüther
Journal:  Development       Date:  2002-07       Impact factor: 6.868

10.  A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules.

Authors:  Lorenza Ciani; Olga Krylova; Matthew J Smalley; Trevor C Dale; Patricia C Salinas
Journal:  J Cell Biol       Date:  2004-01-19       Impact factor: 10.539
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  54 in total

Review 1.  microRNA regulation of Wnt signaling pathways in development and disease.

Authors:  Jia L Song; Priya Nigam; Senel S Tektas; Erica Selva
Journal:  Cell Signal       Date:  2015-04-02       Impact factor: 4.315

2.  Expanding the Spectrum of BAF-Related Disorders: De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay.

Authors:  Keren Machol; Justine Rousseau; Sophie Ehresmann; Thomas Garcia; Thi Tuyet Mai Nguyen; Rebecca C Spillmann; Jennifer A Sullivan; Vandana Shashi; Yong-Hui Jiang; Nicholas Stong; Elise Fiala; Marcia Willing; Rolph Pfundt; Tjitske Kleefstra; Megan T Cho; Heather McLaughlin; Monica Rosello Piera; Carmen Orellana; Francisco Martínez; Alfonso Caro-Llopis; Sandra Monfort; Tony Roscioli; Cheng Yee Nixon; Michael F Buckley; Anne Turner; Wendy D Jones; Peter M van Hasselt; Floris C Hofstede; Koen L I van Gassen; Alice S Brooks; Marjon A van Slegtenhorst; Katherine Lachlan; Jessica Sebastian; Suneeta Madan-Khetarpal; Desai Sonal; Naidu Sakkubai; Julien Thevenon; Laurence Faivre; Alice Maurel; Slavé Petrovski; Ian D Krantz; Jennifer M Tarpinian; Jill A Rosenfeld; Brendan H Lee; Philippe M Campeau
Journal:  Am J Hum Genet       Date:  2018-12-20       Impact factor: 11.025

3.  Wnt/PCP signalling cascade disruption by JNK inhibition as a potential mechanism underlying the teratogenic effects of potato glycoalkaloids.

Authors:  Andrea Cuschieri; Jean Calleja-Agius
Journal:  Mol Biol Rep       Date:  2020-10-24       Impact factor: 2.316

4.  WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene TCF4.

Authors:  Krista M Hennig; Daniel M Fass; Wen-Ning Zhao; Steven D Sheridan; Ting Fu; Serkan Erdin; Alexei Stortchevoi; Diane Lucente; Jannine D Cody; David Sweetser; James F Gusella; Michael E Talkowski; Stephen J Haggarty
Journal:  Mol Neuropsychiatry       Date:  2017-07-14

5.  Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway.

Authors:  Shashi Kant Tiwari; Swati Agarwal; Brashket Seth; Anuradha Yadav; Ratan Singh Ray; Vijay Nath Mishra; Rajnish Kumar Chaturvedi
Journal:  Mol Neurobiol       Date:  2014-11-09       Impact factor: 5.590

Review 6.  Wnt and lithium: a common destiny in the therapy of nervous system pathologies?

Authors:  Delphine Meffre; Julien Grenier; Sophie Bernard; Françoise Courtin; Todor Dudev; Ghjuvan'Ghjacumu Shackleford; Mehrnaz Jafarian-Tehrani; Charbel Massaad
Journal:  Cell Mol Life Sci       Date:  2013-06-09       Impact factor: 9.261

7.  Plasma dickkopf-related protein 1, an antagonist of the Wnt pathway, is associated with HIV-associated neurocognitive impairment.

Authors:  Chunjiang Yu; Melanie Seaton; Scott Letendre; Robert Heaton; Lena Al-Harthi
Journal:  AIDS       Date:  2017-06-19       Impact factor: 4.177

8.  MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.

Authors:  Akshay Bhinge; Jeremie Poschmann; Seema C Namboori; Xianfeng Tian; Sharon Jia Hui Loh; Anna Traczyk; Shyam Prabhakar; Lawrence W Stanton
Journal:  EMBO J       Date:  2014-05-06       Impact factor: 11.598

9.  Gene expression data reveal common pathways that characterize the unifocal nature of ovarian cancer.

Authors:  Douglas C Marchion; Yin Xiong; Hye Sook Chon; Entidhar Al Sawah; Nadim Bou Zgheib; Ingrid J Ramirez; Forough Abbasi; Xiaomang B Stickles; Patricia L Judson; Ardeshir Hakam; Jesus Gonzalez-Bosquet; Robert M Wenham; Sachin M Apte; Anders E Berglund; Johnathan M Lancaster
Journal:  Am J Obstet Gynecol       Date:  2013-08-09       Impact factor: 8.661

Review 10.  Wnt/β-catenin and its diverse physiological cell signaling pathways in neurodegenerative and neuropsychiatric disorders.

Authors:  Lena Al-Harthi
Journal:  J Neuroimmune Pharmacol       Date:  2012-11-01       Impact factor: 4.147
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