Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents.

Literature DB >> 23015068

Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents.

Stephanie J Lucas¹, Rianne M Lord, Rachel L Wilson, Roger M Phillips, Visuvanathar Sridharan, Patrick C McGowan.

Abstract

Several Ru-arene and Ir-Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2012 PMID： 23015068 DOI： 10.1039/c2dt32104a

Source DB: PubMed Journal: Dalton Trans ISSN： 1477-9226 Impact factor: 4.390

Keyword Cloud
Cited

8 in total

1. Impact of various lipophilic substituents on ruthenium(II), rhodium(III) and iridium(III) salicylaldimine-based complexes: synthesis, in vitro cytotoxicity studies and DNA interactions.

Authors: Irwin Cassells; Tameryn Stringer; Alan T Hutton; Sharon Prince; Gregory S Smith
Journal: J Biol Inorg Chem Date: 2018-05-30 Impact factor: 3.358

2. Synthesis and evaluation of new salicylaldehyde-2-picolinylhydrazone Schiff base compounds of Ru(II), Rh(III) and Ir(III) as in vitro antitumor, antibacterial and fluorescence imaging agents.

Authors: Narasinga Rao Palepu; S L Nongbri; J Richard Premkumar; Akalesh Kumar Verma; Kaushik Bhattacharjee; S R Joshi; Scott Forbes; Yurij Mozharivskyj; Romita Thounaojam; K Aguan; Mohan Rao Kollipara
Journal: J Biol Inorg Chem Date: 2015-02-25 Impact factor: 3.358

3. Novel iridium(III) iminopyridine complexes: synthetic, catalytic, and in vitro anticancer activity studies.

Authors: Deliang Kong; Meng Tian; Lihua Guo; Xicheng Liu; Shumiao Zhang; Yameng Song; Xin Meng; Shu Wu; Lingzi Zhang; Zhe Liu
Journal: J Biol Inorg Chem Date: 2018-06-11 Impact factor: 3.358

4. Contrasting Anticancer Activity of Half-Sandwich Iridium(III) Complexes Bearing Functionally Diverse 2-Phenylpyridine Ligands.

Authors: Adam J Millett; Abraha Habtemariam; Isolda Romero-Canelón; Guy J Clarkson; Peter J Sadler
Journal: Organometallics Date: 2015-03-25 Impact factor: 3.876

Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents.

1. Impact of various lipophilic substituents on ruthenium(II), rhodium(III) and iridium(III) salicylaldimine-based complexes: synthesis, in vitro cytotoxicity studies and DNA interactions.

2. Synthesis and evaluation of new salicylaldehyde-2-picolinylhydrazone Schiff base compounds of Ru(II), Rh(III) and Ir(III) as in vitro antitumor, antibacterial and fluorescence imaging agents.

3. Novel iridium(III) iminopyridine complexes: synthetic, catalytic, and in vitro anticancer activity studies.

4. Contrasting Anticancer Activity of Half-Sandwich Iridium(III) Complexes Bearing Functionally Diverse 2-Phenylpyridine Ligands.

5. Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N-Chelated and Pyridine Ligands.

6. Systematic Study on the Cytotoxic Potency of Commonly Used Dimeric Metal Precursors in Human Cancer Cell Lines.

Review 7. Current status of iridium-based complexes against lung cancer.

Review 8. Organoiridium complexes: anticancer agents and catalysts.

Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents.

1. Impact of various lipophilic substituents on ruthenium(II), rhodium(III) and iridium(III) salicylaldimine-based complexes: synthesis, in vitro cytotoxicity studies and DNA interactions.

2. Synthesis and evaluation of new salicylaldehyde-2-picolinylhydrazone Schiff base compounds of Ru(II), Rh(III) and Ir(III) as in vitro antitumor, antibacterial and fluorescence imaging agents.

3. Novel iridium(III) iminopyridine complexes: synthetic, catalytic, and in vitro anticancer activity studies.

4. Contrasting Anticancer Activity of Half-Sandwich Iridium(III) Complexes Bearing Functionally Diverse 2-Phenylpyridine Ligands.

5. Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C∧N-Chelated and Pyridine Ligands.

6. Systematic Study on the Cytotoxic Potency of Commonly Used Dimeric Metal Precursors in Human Cancer Cell Lines.

Review 7. Current status of iridium-based complexes against lung cancer.

Review 8. Organoiridium complexes: anticancer agents and catalysts.

5. Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N-Chelated and Pyridine Ligands.