Literature DB >> 23014969

Long-term survival from 801 adjunctive coronary endarterectomies in diffuse coronary artery disease.

Priyadharshanan Ariyaratnam1, Kalyana Javangula, Sotiris Papaspyros, Evie McCrum-Gardner, Ramanpillai Unnikrishanan Nair.   

Abstract

OBJECTIVES: The role of coronary endarterectomy (CE) in modern cardiac surgery has been an extant debate as coronary artery bypass grafting (CABG) has advanced. However, as cardiac surgeons are being referred ever more complex coronary disease for surgical correction, adjunctive strategies may need re-evaluation. The long-term results of CE are largely unknown. We present the longest cohort follow-up in a single institution looking at our 20-year experience of CEs employed as an adjunct to CABG in diffuse coronary artery disease.
METHODS: We performed retrospective analysis of data collected prospectively on 801 patients undergoing CEs between February 1988 and September 2010 by a single surgeon using a standard open hydrodissection technique. We looked at patient demographics, characteristics of the vessels subjected to endarterectomy and predictors of long-term survival within this surgical group using Cox's regression analysis.
RESULTS: The mean age was 63.2 (±9.6) years. The mean number of coronary arteries undergoing endarterectomy was 1.16 (±0.4) per patient. Of these, 63.7% were performed on the right coronary artery (n = 558) and 32.3% on the left anterior descending artery (n = 283). The operative mortality was 2.62% (n = 21). The median survival time was 16.67 years (95% confidence interval 15.14-18.19 years). The significant predictors of survival (P < 0.05) were a lower age at surgery, a lower EuroSCORE I, the absence of peripheral vascular disease and shorter bypass times.
CONCLUSION: This significant long-term survival demonstrates that CE can be an attractive adjunct to CABG in otherwise inoperable coronary artery disease.

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Year:  2012        PMID: 23014969     DOI: 10.1093/ejcts/ezs510

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  4 in total

Review 1.  Coronary endarterectomy for the diffusely diseased coronary artery.

Authors:  Kosaku Nishigawa; Toshihiro Fukui; Shuichiro Takanashi
Journal:  Gen Thorac Cardiovasc Surg       Date:  2014-05-10

Review 2.  Coronary Endarterectomy: Recent Trends.

Authors:  Ravi Ghatanatti; Anita Teli
Journal:  J Clin Diagn Res       Date:  2017-08-01

3.  Early results of coronary endarterectomy combined with coronary artery bypass grafting in patients with diffused coronary artery disease.

Authors:  Li-Qun Chi; Jian-Qun Zhang; Qing-Yu Kong; Wei Xiao; Lin Liang; Xin-Liang Chen
Journal:  Chin Med J (Engl)       Date:  2015-06-05       Impact factor: 2.628

4.  Open Coronary Endarterectomy of Left Anterior Descending Artery-Case Report and Review of Literature.

Authors:  Mircea Robu; Diana Romina Marian; Ecaterina Lazăr; Răzvan Radu; Cristian Boroș; Andra Sibișan; Cristian Voica; Marian Broască; Daniela Gheorghiță; Horațiu Moldovan; Vlad Anton Iliescu
Journal:  J Cardiovasc Dev Dis       Date:  2022-03-13
  4 in total

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