PURPOSE: To investigate imaging characteristics of post-embolised meningioma and to determine if SW imaging can delineate tumour ischaemia. MATERIALS AND METHODS: Sixteen patients were studied before and after preoperative embolisation therapy (8 histopathologically determined with ischaemia, 8 with non-ischaemia). In each patient, a slice-wise ROI for the entire tumour was established, and histogram variables (mean, SD, minimum, maximum, histogram width, mode, and peak height) of SW, ADC, CBV, CBF, MTT, and TTP maps were compared between ischaemic and non-ischaemic groups. Changes in SW histogram were correlated with histopathological characteristics. RESULTS: Signal intensity on the SW map tended to decrease in the ischaemic group and partially increased in the non-ischaemic group. A similar trend was observed on the ADC map. The PW histogram showed an MTT increase in ischaemic group; however, CBV did not show significant changes between ischaemic and non-ischaemic groups. Microhaemorrhage was slightly correlated with Δpeak height in the SW histogram. CONCLUSION: Post-embolisation changes of intrinsic T2-weighted MR contrasts on SW map are most likely associated with alterations in deoxyhaemoglobin levels and arterial blood flow.
PURPOSE: To investigate imaging characteristics of post-embolised meningioma and to determine if SW imaging can delineate tumour ischaemia. MATERIALS AND METHODS: Sixteen patients were studied before and after preoperative embolisation therapy (8 histopathologically determined with ischaemia, 8 with non-ischaemia). In each patient, a slice-wise ROI for the entire tumour was established, and histogram variables (mean, SD, minimum, maximum, histogram width, mode, and peak height) of SW, ADC, CBV, CBF, MTT, and TTP maps were compared between ischaemic and non-ischaemic groups. Changes in SW histogram were correlated with histopathological characteristics. RESULTS: Signal intensity on the SW map tended to decrease in the ischaemic group and partially increased in the non-ischaemic group. A similar trend was observed on the ADC map. The PW histogram showed an MTT increase in ischaemic group; however, CBV did not show significant changes between ischaemic and non-ischaemic groups. Microhaemorrhage was slightly correlated with Δpeak height in the SW histogram. CONCLUSION: Post-embolisation changes of intrinsic T2-weighted MR contrasts on SW map are most likely associated with alterations in deoxyhaemoglobin levels and arterial blood flow.
Authors: Whitney B Pope; Hyun J Kim; Jing Huo; Jeffry Alger; Matthew S Brown; David Gjertson; Victor Sai; Jonathan R Young; Leena Tekchandani; Timothy Cloughesy; Paul S Mischel; Albert Lai; Phioanh Nghiemphu; Syed Rahmanuddin; Jonathan Goldin Journal: Radiology Date: 2009-07 Impact factor: 11.105
Authors: Sonia P Li; N Jane Taylor; Andreas Makris; Mei-Lin W Ah-See; Mark J Beresford; J James Stirling; James A d'Arcy; David J Collins; Anwar R Padhani Journal: Radiology Date: 2010-09-21 Impact factor: 11.105
Authors: Randall T Higashida; Anthony J Furlan; Heidi Roberts; Thomas Tomsick; Buddy Connors; John Barr; William Dillon; Steven Warach; Joseph Broderick; Barbara Tilley; David Sacks Journal: Stroke Date: 2003-07-17 Impact factor: 7.914
Authors: Emerson L Gasparetto; Mikolaj A Pawlak; Sohil H Patel; Jason Huse; John H Woo; Jaroslaw Krejza; Myrna R Rosenfeld; Donald M O'Rourke; Robert Lustig; Elias R Melhem; Ronald L Wolf Journal: Radiology Date: 2009-03 Impact factor: 11.105
Authors: Alex Rovira; Patricia Orellana; Jose Alvarez-Sabín; Juan F Arenillas; Xavier Aymerich; Elisenda Grivé; Carlos Molina; Antoni Rovira-Gols Journal: Radiology Date: 2004-06-23 Impact factor: 11.105