PURPOSE OF REVIEW: Obesity is a major driver of the current epidemic of chronic kidney disease (CKD), but metrics of obesity in the CKD population have been studied sparsely. This review updates knowledge on this issue. RECENT FINDINGS: Measures of abdominal obesity, waist circumference and waist-to-hip ratio (WHR), are better predictors than BMI of the high risk of mortality in predialysis and dialysis patients and waist circumference reliably reflects visceral fat in CKD patients. Skinfold thickness and WHR are superior to BMI for the classification of obesity in CKD patients. Multifrequency body impedance analysis (BIA) provides valid estimates of fat mass in hemodialysis patients. SUMMARY: Skinfold thickness,WHR and multifrequency BIA are superior to BMI for measuring body fat in CKD patients and measures of abdominal obesity are stronger predictors of adverse clinical outcomes than the BMI. These metrics should be preferentially applied for the assessment of obesity in CKD, but it remains unproven that these techniques offer real advantages over the BMI in clinical practice in CKD patients.
PURPOSE OF REVIEW: Obesity is a major driver of the current epidemic of chronic kidney disease (CKD), but metrics of obesity in the CKD population have been studied sparsely. This review updates knowledge on this issue. RECENT FINDINGS: Measures of abdominal obesity, waist circumference and waist-to-hip ratio (WHR), are better predictors than BMI of the high risk of mortality in predialysis and dialysis patients and waist circumference reliably reflects visceral fat in CKDpatients. Skinfold thickness and WHR are superior to BMI for the classification of obesity in CKDpatients. Multifrequency body impedance analysis (BIA) provides valid estimates of fat mass in hemodialysis patients. SUMMARY: Skinfold thickness,WHR and multifrequency BIA are superior to BMI for measuring body fat in CKDpatients and measures of abdominal obesity are stronger predictors of adverse clinical outcomes than the BMI. These metrics should be preferentially applied for the assessment of obesity in CKD, but it remains unproven that these techniques offer real advantages over the BMI in clinical practice in CKDpatients.
Authors: Hiren P Patel; Jeffrey M Saland; Derek K Ng; Shuai Jiang; Bradley A Warady; Susan L Furth; Joseph T Flynn Journal: J Pediatr Date: 2017-12 Impact factor: 4.406
Authors: Iván Cabezas-Rodriguez; Juan Jesús Carrero; Carmine Zoccali; Abdul Rashid Qureshi; Markus Ketteler; Jürgen Floege; Gérard London; Francesco Locatelli; José Luis Gorriz; Boleslaw Rutkowski; Dimitrios Memmos; Anibal Ferreira; Adrian Covic; Vladimir Teplan; Willem-Jan Bos; Reinhard Kramar; Drasko Pavlovic; David Goldsmith; Judit Nagy; Miha Benedik; Dierik Verbeelen; Christian Tielemans; Rudolf P Wüthrich; Pierre-Yves Martin; Carlos Martínez-Salgado; José Luis Fernández-Martín; Jorge B Cannata-Andia Journal: Clin J Am Soc Nephrol Date: 2013-09-05 Impact factor: 8.237
Authors: Se Won Oh; Shin Young Ahn; Xu Jianwei; Ki Woong Kim; Sejoong Kim; Ki Young Na; Dong Wan Chae; Suhnggwon Kim; Ho Jun Chin Journal: PLoS One Date: 2014-01-16 Impact factor: 3.240