Literature DB >> 23009955

Analysis of cognitive, functional, health service use, and cost trajectories prior to and following memory loss.

Joseph E Gaugler1, Martha Hovater, David L Roth, Joseph A Johnston, Robert L Kane, Khaled Sarsour.   

Abstract

OBJECTIVES: This brief report examines whether significant changes in cognition, functional dependence, health service use, and out-of-pocket medical expenditures (OOPMD) occur in the years prior to a physician-identified memory problem in a nationally representative sample of older adults.
METHOD: Longitudinal data from the RAND-Health and Retirement Survey were utilized. Those who reported a physician-identified memory problem (n = 387) were compared with a randomly selected control group of similar age, race, and gender who did not indicate a memory problem (n = 387). Multilevel linear models were used to construct trajectories for various measures of cognition, function, health service use, and OOPMD in the years prior to and following memory problem identification.
RESULTS: Several trajectories demonstrated significant rates of change in the years leading up to a physician-identified memory problem, including symptoms (mental status, fine motor skills, and instrumental activities of daily living) and utilization (OOPMD and overnight stays in hospital). DISCUSSION: Preclinical declines in mental status and function and increases in hospital use and OOPMD are apparent prior to the formal identification of memory problems. Earlier identification of these changes might provide a basis for interventions that could alter the clinical course of dementia.

Entities:  

Keywords:  Alzheimer’s disease; Diagnosis; Preclinical; Prodromal.

Mesh:

Year:  2012        PMID: 23009955     DOI: 10.1093/geronb/gbs078

Source DB:  PubMed          Journal:  J Gerontol B Psychol Sci Soc Sci        ISSN: 1079-5014            Impact factor:   4.077


  9 in total

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Authors:  Carolyn W Zhu; Stephanie Cosentino; Katherine Ornstein; Yian Gu; Nikolaos Scarmeas; Howard Andrews; Yaakov Stern
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2.  The Moderating Effect of Personality Type on the Relationship between Leisure Activity and Executive Control in Older Adults.

Authors:  Nikki L Hill; Feng Vankee Lin; Jeanine M Parisi; Ann Kolanowski
Journal:  Act Adapt Aging       Date:  2015-01-24

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Authors:  Karen M Lau; Mili Parikh; Danielle J Harvey; Chun-Jung Huang; Sarah Tomaszewski Farias
Journal:  J Int Neuropsychol Soc       Date:  2015-09-22       Impact factor: 2.892

4.  Medicare expenditures attributable to dementia.

Authors:  Lindsay White; Paul Fishman; Anirban Basu; Paul K Crane; Eric B Larson; Norma B Coe
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6.  Nursing Home Use Across The Spectrum of Cognitive Decline: Merging Mayo Clinic Study of Aging With CMS MDS Assessments.

Authors:  Jane A Emerson; Carin Y Smith; Kirsten H Long; Jeanine E Ransom; Rosebud O Roberts; Steven L Hass; Amy M Duhig; Ronald C Petersen; Cynthia L Leibson
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7.  Development of a machine learning model to predict mild cognitive impairment using natural language processing in the absence of screening.

Authors:  Robert B Penfold; David S Carrell; David J Cronkite; Chester Pabiniak; Tammy Dodd; Ashley Mh Glass; Eric Johnson; Ella Thompson; H Michael Arrighi; Paul E Stang
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8.  Regional Hypoperfusion Predicts Decline in Everyday Functioning at Three-Year Follow-Up in Older Adults without Dementia.

Authors:  Danielle L Sanchez; Kelsey R Thomas; Emily C Edmonds; Mark W Bondi; Katherine J Bangen
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9.  Racial and ethnic patterns and differences in health care expenditures among Medicare beneficiaries with and without cognitive deficits or Alzheimer's disease and related dementias.

Authors:  Sungchul Park; Jie Chen
Journal:  BMC Geriatr       Date:  2020-11-18       Impact factor: 3.921

  9 in total

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