Literature DB >> 23009890

Rotational autokeratoplasty in pediatric patients for nonprogressive paracentral corneal scars.

Muralidhar Ramappa1, Niranjan K Pehere, Somasheila I Murthy, Sunita Chaurasia, Harsha L Rao, Virender S Sangwan.   

Abstract

OBJECTIVE: To report the outcomes of ipsilateral rotational autokeratoplasty (RAK) for nonprogressive paracentral corneal opacities in children <16 years of age.
DESIGN: Retrospective, consecutive, interventional case series. PARTICIPANTS: Thirty-three eyes of 33 children aged <16 years undergoing RAK for nonprogressive paracentral scars.
METHODS: Medical records were retrospectively reviewed for the primary etiology of corneal opacity, time of onset, duration of opacity, preoperative visual acuity, formula used for calculation of trephine size, size of the trephine used, and duration of follow-up. Any intraoperative and early and late postoperative complications were noted for all patients. Postoperative visual acuity and astigmatism were noted. Visual acuity was converted to logarithm of the minimum angle of resolution units for analysis. MAIN OUTCOME MEASURES: Primary outcome was postoperative visual acuity. Graft clarity and complications were analyzed as secondary outcomes.
RESULTS: The mean age at surgery was 7.2 ± 3 .9 months. The mean follow-up duration was 27 ± 37 months. The commonest etiology of corneal opacity was trauma (62.5%), followed by resolved microbial keratitis (21.9%). Postoperative visual acuity (1.25 ± 0.84) was significantly better (P<0.001) than preoperative visual acuity (2.05 ± 0.96). The mean astigmatism at last visit was 4.04 ± 2.21 diopters. Postoperative visual acuity was better in older children (β = -0.01; P = 0.03) and had a shorter delay in presentation (β = 0.02; P = 0.05). At the last follow-up, the graft was clear in 27 cases (81.25%). The cumulative probability of graft survival was 85% at 2 years and 65% at 5 years. Complications included wound leak in 4 eyes, secondary glaucoma in 2 eyes, graft infiltrate and traumatic dehiscence in 1 eye each.
CONCLUSIONS: Rotational is a autokeratoplasty viable alternative surgical option to allogenic keratoplasty. Graft survival at 2 years seems to be better than allogenic keratoplasty. Younger age and delay in presentation contribute to poorer visual outcomes after surgery. FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any of the materials discussed in this article.
Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23009890     DOI: 10.1016/j.ophtha.2012.06.045

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  2 in total

1.  Contralateral Autokeratoplasty, Pars Plana Vitrectomy for Luxated Cataract, and Flanged Intrascleral Intraocular Lens Fixation.

Authors:  Francisco Lucero Saá; Federico Andrés Cremona; Mariano Cotic; Pablo Chiaradía
Journal:  J Curr Ophthalmol       Date:  2022-04-16

2.  Indications and outcomes of pediatric keratoplasty in a tertiary eye care center: A retrospective review.

Authors:  Rosario Gulias-Cañizo; Roberto Gonzalez-Salinas; Luis Fernando Hernandez-Zimbron; Everardo Hernandez-Quintela; Valeria Sanchez-Huerta
Journal:  Medicine (Baltimore)       Date:  2017-11       Impact factor: 1.817

  2 in total

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