| Literature DB >> 23008096 |
Bryan Laulicht1, Alexis Mancini, Nathanael Geman, Daniel Cho, Kenneth Estrellas, Stacia Furtado, Russell Hopson, Anubhav Tripathi, Edith Mathiowitz.
Abstract
The one-step synthesis and characterization of novel bioinspired bioadhesive polymers that contain Dopa, implicated in the extremely adhesive byssal fibers of certain gastropods, is reported. The novel polymers consist of combinations of either of two polyanhydride backbones and one of three amino acids, phenylalanine, tyrosine, or Dopa, grafted as side chains. Dopa-grafted hydrophobic backbone polymers exhibit as much as 2.5 × the fracture strength and 2.8 × the tensile work of bioadhesion of a commercially available poly(acrylic acid) derivative as tested on live, excised, rat intestinal tissue.Entities:
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Year: 2012 PMID: 23008096 DOI: 10.1002/mabi.201200179
Source DB: PubMed Journal: Macromol Biosci ISSN: 1616-5187 Impact factor: 4.979