| Literature DB >> 23007701 |
Abstract
Whether dominantly inherited variants of Alzheimer disease (AD) and 'sporadic' forms exhibit similar pathophysiological and biomarker signatures remains unresolved. A landmark study has proposed a biomarker progression model of dominantly inherited AD, but a complex systems biology and physiology approach is required to translate these findings to sporadic disease.Entities:
Mesh:
Substances:
Year: 2012 PMID: 23007701 DOI: 10.1038/nrneurol.2012.202
Source DB: PubMed Journal: Nat Rev Neurol ISSN: 1759-4758 Impact factor: 42.937