Literature DB >> 23007418

Life-threatening agranulocytosis, anemia, and plasmacytosis after dipyrone use for fever in a child.

Melek Işık1, Zuhre Kaya, Fatma Burcu Belen, Anıl Tapısız Aktaş, Hasan Tezer, Türkiz Gürsel.   

Abstract

Dipyrone or metamizole Na (Novalgin) is commonly used as an antipyretic, analgesic, and spasmolytic agent in some parts of the world; however, it is banned in developed countries because of severe side effects. Here we present a case of a 4-year-old boy who developed life-threatening agranulocytosis, anemia, and marked plasmacytosis in his bone marrow after dipyrone use for fever, which resolved with steroid therapy.

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Year:  2014        PMID: 23007418     DOI: 10.1097/MPH.0b013e31826e7d9d

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN: 1077-4114            Impact factor:   1.289


  3 in total

1.  Metamizole-induced agranulocytosis revisited: results from the prospective Berlin Case-Control Surveillance Study.

Authors:  Matthias Huber; Frank Andersohn; Giselle Sarganas; Elisabeth Bronder; Andreas Klimpel; Michael Thomae; Christine Konzen; Reinhold Kreutz; Edeltraut Garbe
Journal:  Eur J Clin Pharmacol       Date:  2014-11-08       Impact factor: 2.953

2.  [Perioperative use of metamizole and other nonopioid analgesics in children : Results of a survey].

Authors:  L Witschi; L Reist; T Stammschulte; J Erlenwein; K Becke; U Stamer
Journal:  Anaesthesist       Date:  2019-01-24       Impact factor: 1.041

3.  Metamizole Use in Children: Analysis of Drug Utilisation and Adverse Drug Reactions at a German University Hospital between 2015 and 2020.

Authors:  Julia Zahn; Sonja Eberl; Wolfgang Rödle; Wolfgang Rascher; Antje Neubert; Irmgard Toni
Journal:  Paediatr Drugs       Date:  2021-12-08       Impact factor: 3.022

  3 in total

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