Literature DB >> 2300719

Attenuation of Borrelia anserina by serial passage in liquid medium.

J F Levine1, M J Dykstra, W L Nicholson, R L Walker, G Massey, H J Barnes.   

Abstract

Borrelia anserina (Sakharoff) was successfully grown in a liquid medium (Barbour-Stoenner-Kelly) for 39 passages. By the 12th serial passage in medium, infectivity of B anserina for chicks was lost. Electron microscopy did not reveal structural differences between non-infective and infective cultured organisms. Changes in the protein profiles were found by electrophoresis as the organisms were passed in culture.

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Year:  1990        PMID： 2300719

Source DB:  PubMed          Journal:  Res Vet Sci        ISSN： 0034-5288            Impact factor:   2.534


  3 in total

1.  Specific antibodies reactive with the 22-kilodalton major outer surface protein of Borrelia anserina Ni-NL protect chicks from infection.

Authors:  V Sambri; A Marangoni; A Olmo; E Storni; M Montagnani; M Fabbi; R Cevenini
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

2.  Natural infections with Borrelia spirochetes in two dogs from Florida.

Authors:  E B Breitschwerdt; W L Nicholson; A R Kiehl; C Steers; D J Meuten; J F Levine
Journal:  J Clin Microbiol       Date:  1994-02       Impact factor: 5.948

3.  Relapsing fever spirochetes retain infectivity after prolonged in vitro cultivation.

Authors:  Job E Lopez; Merry E Schrumpf; Sandra J Raffel; Paul F Policastro; Stephen F Porcella; Tom G Schwan
Journal:  Vector Borne Zoonotic Dis       Date:  2008-12       Impact factor: 2.133
  3 in total

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