Literature DB >> 23006595

Perioperative risk factors for deep vein thrombosis after total hip arthroplasty or total knee arthroplasty.

Yuichiro Shimoyama1, Toshiyuki Sawai, Shinichi Tatsumi, Junko Nakahira, Masayuki Oka, Mikio Nakajima, Tsuyoshi Jotoku, Toshiaki Minami.   

Abstract

STUDY
OBJECTIVE: To determine the perioperative frequency of deep vein thrombosis (DVT) after lower limb joint prosthesis surgery using Doppler ultrasonography (US).
DESIGN: Prospective cohort study.
SETTING: Operating room and hospital ward. PATIENTS: 144 consecutive ASA physical status 1 and 2 patients who underwent elective total hip arthroplasty (THA; n=64) or total knee arthroplasty (TKA; n= 80).
INTERVENTIONS: Patients were allocated to two groups, those who developed DVT (DVT group) postoperatively and those who did not (no-DVT group). To examine the perioperative risk factors for DVT after THA or TKA, comparative analysis of the two groups was done. MEASUREMENTS: Doppler US was performed on all patients from the bilateral femoral to lower limb to detect the existence of DVT postoperatively. MAIN
RESULTS: DVT was detected in 61 patients (42%), including three proximal DVT patients (2%). Preoperative elevated plasma D-dimer value [P = 0.0131, odds ratio (OR) 1.54, 95% CI 1.10-2.17] and history of hyperlipidemia (P = 0.0453, OR 6.92, 95% CI 1.04-46.00] were significant risk factors for the onset of DVT. A preoperative plasma D-dimer cutoff value as a diagnostic test was obtained as 0.85 μg/mL.
CONCLUSIONS: A high preoperative plasma D-dimer value and/or history of hyperlipidemia were risk factors for DVT after THA or TKA.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23006595     DOI: 10.1016/j.jclinane.2012.02.008

Source DB:  PubMed          Journal:  J Clin Anesth        ISSN: 0952-8180            Impact factor:   9.452


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