Literature DB >> 23000137

The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.

Nunziata Barbera1, Francesco Paolo Busardò, Francesca Indorato, Guido Romano.   

Abstract

The purpose of the present study is to determine the role of lidocaine, caffeine and dextromethorphan, used as adulterant substances, in five cases of drug overdose which have come to our attention. Taking into account the pharmacological mechanism, blood concentration and route of administration (intravenous) we evaluated the hypothesis that these substances could act with a synergistic effect - or at least additive - with the illicit drugs on the central nervous system and cardiovascular system.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 23000137     DOI: 10.1016/j.forsciint.2012.08.041

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  5 in total

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  5 in total

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