Literature DB >> 22999810

NF-κB and hypoxia: a double-edged sword in atherosclerosis.

Xinghui Sun1, Mark W Feinberg.   

Abstract

This Commentary highlights the article by Fang et al, which describes novel mouse models of chronic intermittent hypoxia (CIH)-induced atherosclerosis, revealing that loss of the NF-κB p50 subunit increased atherosclerosis in the presence of CIH.
Copyright © 2012 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22999810      PMCID： PMC3483811          DOI： 10.1016/j.ajpath.2012.09.001

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


  45 in total

1.  Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.

Authors:  Eoin P Cummins; Edurne Berra; Katrina M Comerford; Amandine Ginouves; Kathleen T Fitzgerald; Fergal Seeballuck; Catherine Godson; Jens E Nielsen; Paul Moynagh; Jacques Pouyssegur; Cormac T Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-17       Impact factor: 11.205

2.  MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro.

Authors:  Yun Fang; Congzhu Shi; Elisabetta Manduchi; Mete Civelek; Peter F Davies
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-12       Impact factor: 11.205

3.  Chronic intermittent hypoxia induces atherosclerosis.

Authors:  Vladimir Savransky; Ashika Nanayakkara; Jianguo Li; Shannon Bevans; Philip L Smith; Annabelle Rodriguez; Vsevolod Y Polotsky
Journal:  Am J Respir Crit Care Med       Date:  2007-03-01       Impact factor: 21.405

Review 4.  Obstructive sleep apnea and dyslipidemia: implications for atherosclerosis.

Authors:  Luciano F Drager; Jonathan Jun; Vsevolod Y Polotsky
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2010-04       Impact factor: 3.243

5.  Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.

Authors:  Ralph Gareus; Elena Kotsaki; Sofia Xanthoulea; Ingeborg van der Made; Marion J J Gijbels; Rozina Kardakaris; Apostolos Polykratis; George Kollias; Menno P J de Winther; Manolis Pasparakis
Journal:  Cell Metab       Date:  2008-11       Impact factor: 27.287

6.  Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

Authors:  Chiara Porta; Monica Rimoldi; Geert Raes; Lea Brys; Pietro Ghezzi; Diana Di Liberto; Francesco Dieli; Serena Ghisletti; Gioacchino Natoli; Patrick De Baetselier; Alberto Mantovani; Antonio Sica
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-17       Impact factor: 11.205

Review 7.  Obstructive sleep apnea, immuno-inflammation, and atherosclerosis.

Authors:  Claire Arnaud; Maurice Dematteis; Jean-Louis Pepin; Jean-Philippe Baguet; Patrick Lévy
Journal:  Semin Immunopathol       Date:  2009-04-29       Impact factor: 9.623

8.  Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice.

Authors:  Jonathan Jun; Christian Reinke; Djahida Bedja; Dan Berkowitz; Shannon Bevans-Fonti; Jianguo Li; Lili A Barouch; Kathleen Gabrielson; Vsevolod Y Polotsky
Journal:  Atherosclerosis       Date:  2009-10-17       Impact factor: 5.162

9.  NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.

Authors:  Jordi Rius; Monica Guma; Christian Schachtrup; Katerina Akassoglou; Annelies S Zinkernagel; Victor Nizet; Randall S Johnson; Gabriel G Haddad; Michael Karin
Journal:  Nature       Date:  2008-04-23       Impact factor: 49.962

10.  Regulation of hypoxia-inducible factor-1alpha by NF-kappaB.

Authors:  Patrick van Uden; Niall S Kenneth; Sonia Rocha
Journal:  Biochem J       Date:  2008-06-15       Impact factor: 3.766
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  2 in total

1.  A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders.

Authors:  Lakshmi Subramanian; Abrar A Khan; Prasanna K R Allu; Malapaka Kiranmayi; Bhavani S Sahu; Saurabh Sharma; Madhu Khullar; Ajit S Mullasari; Nitish R Mahapatra
Journal:  J Biol Chem       Date:  2017-06-30       Impact factor: 5.157

2.  Immune System Modulation by the Adjuvants Poly (I:C) and Montanide ISA 720.

Authors:  Rodolfo F Marques; Filipe Menegatti de Melo; Janaina Tenório Novais; Irene S Soares; Daniel Youssef Bargieri; Alba Marina Gimenez
Journal:  Front Immunol       Date:  2022-06-29       Impact factor: 8.786
  2 in total

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