I B Elgen1, F Holsten, M D Odberg. 1. Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Child and Adolescent Psychiatry, Haukeland University Hospital, Norway; Department of Pediatric, Haukeland University Hospital, Norway. Electronic address: ielg@helse-bergen.no.
Abstract
OBJECTIVE: To compare mental health of 136 young adults without neurosensory handicaps born with low birthweight (LBW, birthweight less than 2,000 g) with 132 adults with normal birthweight (NBW). METHOD: A cohort of moderate LBW and NBW young adults were assessed with the Mini-International Neuropsychiatric Interview (MINI) at 19 years and the Children Assessment Schedule (CAS) at 11 years of age. RESULTS: At 19 years of age, 44 out of 136 (32%) LBW young adults were diagnosed with a psychiatric disorder compared to 10% NBW (OR: 2.8; 95% CI: 1.1, 4.5, P=0.02). Among the LBW young adults, affective-, anxiety-, ADHD- and antisocial personality disorders were most common, and nine subjects (20%) had more than one diagnosis. Of 97 LBW subjects examined both at 11 and 19 years of age, 54 (56%) were mentally healthy though out adolescence. This was half as many as for controls (OR: 0.6; 95% CI: 0.3 to 0.9). CONCLUSION: Moderate LBW was associated with an increased risk of psychiatric disorders in young adulthood. Only half of LBW young adults stayed healthy throughout adolescence.
OBJECTIVE: To compare mental health of 136 young adults without neurosensory handicaps born with low birthweight (LBW, birthweight less than 2,000 g) with 132 adults with normal birthweight (NBW). METHOD: A cohort of moderate LBW and NBW young adults were assessed with the Mini-International Neuropsychiatric Interview (MINI) at 19 years and the Children Assessment Schedule (CAS) at 11 years of age. RESULTS: At 19 years of age, 44 out of 136 (32%) LBW young adults were diagnosed with a psychiatric disorder compared to 10% NBW (OR: 2.8; 95% CI: 1.1, 4.5, P=0.02). Among the LBW young adults, affective-, anxiety-, ADHD- and antisocial personality disorders were most common, and nine subjects (20%) had more than one diagnosis. Of 97 LBW subjects examined both at 11 and 19 years of age, 54 (56%) were mentally healthy though out adolescence. This was half as many as for controls (OR: 0.6; 95% CI: 0.3 to 0.9). CONCLUSION: Moderate LBW was associated with an increased risk of psychiatric disorders in young adulthood. Only half of LBW young adults stayed healthy throughout adolescence.
Authors: Allison M Momany; Jaclyn M Kamradt; Josie M Ullsperger; Alexis L Elmore; Joel T Nigg; Molly A Nikolas Journal: J Abnorm Psychol Date: 2016-11-17
Authors: Christine Henriksen; Astrid N Almaas; Ane C Westerberg; Christian A Drevon; Per O Iversen; Britt Nakstad Journal: Eur J Pediatr Date: 2016-08-09 Impact factor: 3.183