Literature DB >> 22998788

Varicocele in younger as risk factor for inguinal hernia and for chronic venous disease in older: preliminary results of a prospective cohort study.

Raffaele Serra1, Gianluca Buffone, Giuseppe Costanzo, Rossella Montemurro, Paolo Perri, Rocco Damiano, Stefano de Franciscis.   

Abstract

BACKGROUND: Varicocele, inguinal hernia, and chronic venous insufficiency are often associated. Varicocele has its maximum prevalence in younger age, whereas hernia and chronic venous disease appear later. The aim of this study was to analyze the relationship between these conditions.
METHODS: A prospective cohort study was conducted, consisting of two groups of male patients. Group A comprised patients with varicocele, whereas group B comprised those with problems other than varicocele. Both groups were followed over time and were assessed for the onset of signs and symptoms related to inguinal hernia and chronic venous disease.
RESULTS: Preliminary results showed a positive correlation between the presence of varicocele in younger and the possible risk of hernia and/or chronic venous disease in later age.
CONCLUSIONS: Preliminary results suggest that varicocele in younger age appears to be an early marker of progression for a connective tissue-related disease in later age.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22998788     DOI: 10.1016/j.avsg.2012.03.016

Source DB:  PubMed          Journal:  Ann Vasc Surg        ISSN: 0890-5096            Impact factor:   1.466


  12 in total

1.  Effects of a new nutraceutical substance on clinical and molecular parameters in patients with chronic venous ulceration.

Authors:  Raffaele Serra; Raffaele Grande; Lucia Butrico; Gianluca Buffone; Francesco G Caliò; Aida Squillace; Barbara A Rizzo; Mafalda Massara; Francesco Spinelli; Alessia G Ferrarese; Giovanni de Caridi; Luca Gallelli; Stefano de Franciscis
Journal:  Int Wound J       Date:  2014-02-25       Impact factor: 3.315

2.  Extracellular matrix assessment of infected chronic venous leg ulcers: role of metalloproteinases and inflammatory cytokines.

Authors:  Raffaele Serra; Raffaele Grande; Gianluca Buffone; Vincenzo Molinari; Paolo Perri; Aldina Perri; Bruno Amato; Manuela Colosimo; Stefano de Franciscis
Journal:  Int Wound J       Date:  2014-02-19       Impact factor: 3.315

3.  Hyperhomocysteinaemia and chronic venous ulcers.

Authors:  Stefano de Franciscis; Giovambattista De Sarro; Paola Longo; Gianluca Buffone; Vincenzo Molinari; Domenico M Stillitano; Luca Gallelli; Raffaele Serra
Journal:  Int Wound J       Date:  2013-02-19       Impact factor: 3.315

4.  Effectiveness of prostaglandin E1 in patients with mixed arterial and venous ulcers of the lower limbs.

Authors:  Giovanni De Caridi; Mafalda Massara; Francesco Stilo; Francesco Spinelli; Raffaele Grande; Lucia Butrico; Stefano de Franciscis; Raffaele Serra
Journal:  Int Wound J       Date:  2014-08-05       Impact factor: 3.315

5.  From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases.

Authors:  Raffaele Serra; Luca Gallelli; Lucia Butrico; Gianluca Buffone; Francesco G Caliò; Giovanni De Caridi; Mafalda Massara; Andrea Barbetta; Bruno Amato; Miriam Labonia; Selena Mimmi; Enrico Iaccino; Stefano de Franciscis
Journal:  Int Wound J       Date:  2016-03-15       Impact factor: 3.315

6.  Doxycycline speeds up healing of chronic venous ulcers.

Authors:  Raffaele Serra; Luca Gallelli; Gianluca Buffone; Vincenzo Molinari; Domenico M Stillitano; Camillo Palmieri; Stefano de Franciscis
Journal:  Int Wound J       Date:  2013-04-05       Impact factor: 3.315

7.  Role of matrix metalloproteinases in non-healing venous ulcers.

Authors:  Bruno Amato; Guido Coretti; Rita Compagna; Maurizio Amato; Gianluca Buffone; Diego Gigliotti; Raffaele Grande; Raffaele Serra; Stefano de Franciscis
Journal:  Int Wound J       Date:  2013-10-24       Impact factor: 3.315

8.  PredyCLU: a prediction system for chronic leg ulcers based on fuzzy logic; part I - exploring the venous side.

Authors:  Stefano de Franciscis; Salvatore Fregola; Alessandro Gallo; Giuseppe Argirò; Andrea Barbetta; Gianluca Buffone; Francesco G Caliò; Giovanni De Caridi; Bruno Amato; Raffaele Serra
Journal:  Int Wound J       Date:  2015-11-06       Impact factor: 3.315

9.  Trophic effects of polynucleotides and hyaluronic acid in the healing of venous ulcers of the lower limbs: a clinical study.

Authors:  Giovanni De Caridi; Mafalda Massara; Ignazio Acri; Salvatore Zavettieri; Raffaele Grande; Lucia Butrico; Stefano de Franciscis; Raffaele Serra
Journal:  Int Wound J       Date:  2014-09-16       Impact factor: 3.315

10.  The effects of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs.

Authors:  Raffaele Serra; Luca Gallelli; Angela Conti; Giovanni De Caridi; Mafalda Massara; Francesco Spinelli; Gianluca Buffone; Francesco Giuseppe Caliò; Bruno Amato; Simona Ceglia; Giuseppe Spaziano; Luca Scaramuzzino; Alessia Giovanna Ferrarese; Raffaele Grande; Stefano de Franciscis
Journal:  Drug Des Devel Ther       Date:  2014-05-13       Impact factor: 4.162

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