Literature DB >> 22997343

Association of modality with mortality among Canadian Aboriginals.

Manish M Sood1, Brenda Hemmelgarn, Claudio Rigatto, Paul Komenda, Karen Yeates, Steven Promislow, Julie Mojica, Navdeep Tangri.   

Abstract

BACKGROUND AND OBJECTIVES: Previous studies have shown that Aboriginals and Caucasians experience similar outcome on dialysis in Canada. Using the Canadian Organ Replacement Registry, this study examined whether dialysis modality (peritoneal or hemodialysis) impacted mortality in Aboriginal patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This study identified 31,576 adult patients (hemodialysis: Aboriginal=1839, Caucasian=21,430; peritoneal dialysis: Aboriginal=554, Caucasian=6769) who initiated dialysis between January of 2000 and December of 2009. Aboriginal status was identified by self-report. Dialysis modality was determined 90 days after dialysis initiation. Multivariate Cox proportional hazards and competing risk models were constructed to determine the association between race and mortality by dialysis modality.
RESULTS: During the study period, 939 (51.1%) Aboriginals and 12,798 (53.3%) Caucasians initiating hemodialysis died, whereas 166 (30.0%) and 2037 (30.1%), respectively, initiating peritoneal dialysis died. Compared with Caucasians, Aboriginals on hemodialysis had a comparable risk of mortality (adjusted hazards ratio=1.04, 95% confidence interval=0.96-1.11, P=0.37). However, on peritoneal dialysis, Aboriginals experienced a higher risk of mortality (adjusted hazards ratio=1.36, 95% confidence interval=1.13-1.62, P=0.001) and technique failure (adjusted hazards ratio=1.29, 95% confidence interval=1.03-1.60, P=0.03) than Caucasians. The risk of technique failure varied by patient age, with younger Aboriginals (<50 years old) more likely to develop technique failure than Caucasians (adjusted hazards ratio=1.76, 95% confidence interval=1.23-2.52, P=0.002).
CONCLUSIONS: Aboriginals on peritoneal dialysis experience higher mortality and technique failure relative to Caucasians. Reasons for this race disparity in peritoneal dialysis outcomes are unclear.

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Year:  2012        PMID: 22997343      PMCID: PMC3513745          DOI: 10.2215/CJN.03650412

Source DB:  PubMed          Journal:  Clin J Am Soc Nephrol        ISSN: 1555-9041            Impact factor:   8.237


  22 in total

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2.  Regional differences in dialysis care and mortality among American Indians and Alaska Natives.

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3.  Adverse outcomes among Aboriginal patients receiving peritoneal dialysis.

Authors:  Manish M Sood; Paul Komenda; Amy R Sood; Martina Reslerova; Mauro Verrelli; Chris Sathianathan; Loretta Eng; Amanda Eng; Claudio Rigatto
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4.  Dialysis and transplantation among Aboriginal children with kidney failure.

Authors:  Susan M Samuel; Bethany J Foster; Marcello A Tonelli; Alberto Nettel-Aguirre; Andrea Soo; R Todd Alexander; Lynden Crowshoe; Brenda R Hemmelgarn
Journal:  CMAJ       Date:  2011-05-24       Impact factor: 8.262

5.  Association of race and age with survival among patients undergoing dialysis.

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6.  Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study.

Authors:  Joanne M Bargman; Kevin E Thorpe; David N Churchill
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7.  Remote indigenous peritoneal dialysis patients have higher risk of peritonitis, technique failure, all-cause and peritonitis-related mortality.

Authors:  Wai H Lim; Neil Boudville; Stephen P McDonald; Gillian Gorham; David W Johnson; Matthew Jose
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8.  The health of Ontario First Nations people: results from the Ontario First Nations Regional Health Survey.

Authors:  Harriet L MacMillan; Christine A Walsh; Ellen Jamieson; Maria Y Y Wong; Emily J Faries; Harvey McCue; Angus B MacMillan; David Dan R Offord
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9.  Epidemiology of diabetes mellitus among First Nations and non-First Nations adults.

Authors:  Roland Dyck; Nathaniel Osgood; Ting Hsiang Lin; Amy Gao; Mary Rose Stang
Journal:  CMAJ       Date:  2010-01-18       Impact factor: 8.262

10.  Predictors and outcomes of fungal peritonitis in peritoneal dialysis patients.

Authors:  Rhianna Miles; Carmel M Hawley; Stephen P McDonald; Fiona G Brown; Johan B Rosman; Kathryn J Wiggins; Kym M Bannister; David W Johnson
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  7 in total

1.  Geographic and facility-level variation in the use of peritoneal dialysis in Canada: a cohort study.

Authors:  Manish M Sood; Navdeep Tangri; Brett Hiebert; Joanne Kappel; Allison Dart; Adeera Levin; Braden Manns; Anita Molzahn; David Naimark; Sharon J Nessim; Claudio Rigatto; Steven D Soroka; Michael Zappitelli; Paul Komenda
Journal:  CMAJ Open       Date:  2014-03-27

2.  Barriers to Peritoneal Dialysis in Aboriginal Patients.

Authors:  Anna T Mathew; Joonho Park; Mala Sachdeva; Manish M Sood; Karen Yeates
Journal:  Can J Kidney Health Dis       Date:  2018-01-03

3.  Knowledge Translation Interventions to Improve the Timing of Dialysis Initiation: Protocol for a Cluster Randomized Trial.

Authors:  Elaine M T Chau; Braden J Manns; Amit X Garg; Manish M Sood; S Joseph Kim; David Naimark; Gihad E Nesrallah; Steven D Soroka; Monica Beaulieu; Stephanie Dixon; Ahsan Alam; Navdeep Tangri
Journal:  Can J Kidney Health Dis       Date:  2016-09-14

4.  Validation of Self-Reported Race in a Canadian Provincial Renal Administrative Database.

Authors:  Aiza Waheed; Ognjenka Djurdjev; Jianghu Dong; Jagbir Gill; Sean Barbour
Journal:  Can J Kidney Health Dis       Date:  2019-07-01

5.  Is Assisted Peritoneal Dialysis a Solution for Northern Manitoba?

Authors:  Josée G Lavoie; James Zacharias; Joseph Kaufert; Nicholas Krueger; Kathi Avery Kinew; Lorraine Mcleod; Caroline Chartrand
Journal:  Healthc Policy       Date:  2019-05

6.  Reported sources of health inequities in Indigenous Peoples with chronic kidney disease: a systematic review of quantitative studies.

Authors:  Tania Huria; Suzanne G Pitama; Lutz Beckert; Jaquelyne Hughes; Nathan Monk; Cameron Lacey; Suetonia C Palmer
Journal:  BMC Public Health       Date:  2021-07-23       Impact factor: 3.295

7.  Young aboriginals are less likely to receive a renal transplant: a Canadian national study.

Authors:  Steven Promislow; Brenda Hemmelgarn; Claudio Rigatto; Navdeep Tangri; Paul Komenda; Leroy Storsley; Karen Yeates; Julie Mojica; Manish M Sood
Journal:  BMC Nephrol       Date:  2013-01-14       Impact factor: 2.388

  7 in total

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