Literature DB >> 22990806

Assessing transmission blockade in Plasmodium spp.

Andrew M Blagborough1, Michael J Delves, Chandra Ramakrishnan, Kalpana Lal, Geoffrey Butcher, Robert E Sinden.   

Abstract

Here we describe a series of methods that can be used to assess the activities of "vaccines," drugs, and genetically modified vectors, for their abilities to inhibit transmission of Plasmodium from its vertebrate to its mosquito hosts. The selection of method to be used is determined by the purpose of the experiment, which can include the determination of the site/time of activity, and/or the potential reduction in transmission achieved.

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Year:  2013        PMID: 22990806     DOI: 10.1007/978-1-62703-026-7_40

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  23 in total

1.  Chalcones as a basis for computer-aided drug design: innovative approaches to tackle malaria.

Authors:  Marilia Nn Lima; Bruno J Neves; Gustavo C Cassiano; Marcelo N Gomes; Kaira Cp Tomaz; Leticia T Ferreira; Tatyana A Tavella; Juliana Calit; Daniel Y Bargieri; Eugene N Muratov; Fabio Tm Costa; Carolina Horta Andrade
Journal:  Future Med Chem       Date:  2019-09-26       Impact factor: 3.808

Review 2.  New insight-guided approaches to detect, cure, prevent and eliminate malaria.

Authors:  Sushil Kumar; Renu Kumari; Richa Pandey
Journal:  Protoplasma       Date:  2014-10-17       Impact factor: 3.356

Review 3.  Antimalarial drug discovery - approaches and progress towards new medicines.

Authors:  Erika L Flannery; Arnab K Chatterjee; Elizabeth A Winzeler
Journal:  Nat Rev Microbiol       Date:  2013-11-11       Impact factor: 60.633

4.  Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

Authors:  Katharine Trenholme; Linda Marek; Sandra Duffy; Gabriele Pradel; Gillian Fisher; Finn K Hansen; Tina S Skinner-Adams; Alice Butterworth; Che Julius Ngwa; Jonas Moecking; Christopher D Goodman; Geoffrey I McFadden; Subathdrage D M Sumanadasa; David P Fairlie; Vicky M Avery; Thomas Kurz; Katherine T Andrews
Journal:  Antimicrob Agents Chemother       Date:  2014-04-14       Impact factor: 5.191

5.  Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Compounds.

Authors:  Juliana Calit; Irina Dobrescu; Xiomara A Gaitán; Miriam H Borges; Marisé S Ramos; Richard T Eastman; Daniel Y Bargieri
Journal:  Antimicrob Agents Chemother       Date:  2018-10-24       Impact factor: 5.191

6.  Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.

Authors:  Louis-Jérôme Leba; Lise Musset; Stéphane Pelleau; Yannick Estevez; Caroline Birer; Sébastien Briolant; Benoit Witkowski; Didier Ménard; Michael J Delves; Eric Legrand; Christophe Duplais; Jean Popovici
Journal:  Malar J       Date:  2015-06-04       Impact factor: 2.979

7.  Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials.

Authors:  Erika L Flannery; Case W McNamara; Sang Wan Kim; Tomoyo Sakata Kato; Fengwu Li; Christine H Teng; Kerstin Gagaring; Micah J Manary; Rachel Barboa; Stephan Meister; Kelli Kuhen; Joseph M Vinetz; Arnab K Chatterjee; Elizabeth A Winzeler
Journal:  ACS Chem Biol       Date:  2014-11-05       Impact factor: 5.100

Review 8.  Application of multi-target phytotherapeutic concept in malaria drug discovery: a systems biology approach in biomarker identification.

Authors:  Protus Arrey Tarkang; Regina Appiah-Opong; Michael F Ofori; Lawrence S Ayong; Alexander K Nyarko
Journal:  Biomark Res       Date:  2016-12-13

9.  Targeting the Conserved Fusion Loop of HAP2 Inhibits the Transmission of Plasmodium berghei and falciparum.

Authors:  Fiona Angrisano; Katarzyna A Sala; Dari F Da; Yanjie Liu; Jimin Pei; Nick V Grishin; William J Snell; Andrew M Blagborough
Journal:  Cell Rep       Date:  2017-12-05       Impact factor: 9.423

10.  Immunization with Transgenic Rodent Malaria Parasites Expressing Pfs25 Induces Potent Transmission-Blocking Activity.

Authors:  K A Sala; F Angrisano; D F Da; I J Taylor; T S Churcher; A M Blagborough
Journal:  Sci Rep       Date:  2018-01-25       Impact factor: 4.379

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