Literature DB >> 22990377

Cost of HIV and determinants of health care costs in HIV-positive patients in Germany: results of the DAGNÄ K3A Study.

Sarah Mostardt1, Nikola Hanhoff, Jürgen Wasem, Armin Goetzenich, Knud Schewe, Eva Wolf, Christoph Mayr, Hans Jaeger, Holger Pfaff, Stephan Dupke, Anja Neumann.   

Abstract

OBJECTIVES: The aims of this study were to estimate the expenditure for HIV-care in Germany and to identify variables associated with resource use. DESIGN/
SETTING: We performed an 18-month prospective multi-center study in an HIV specialized ambulatory care setting from 2006 to 2009. SUBJECTS, PARTICIPANTS: Patients were eligible for study participation if they (1) were HIV-positive, (2) were ≥ 18 years of age, (3) provided written consent and (4) were not enrolled in another clinical study; 518 patients from 17 centers were included. MAIN OUTCOME MEASURES: Health care costs were estimated following a micro-costing approach from two perspectives: (1) costs incurred to society in general, and (2) costs incurred to statutory health insurance. Data were obtained using questionnaires. Several empirical models for identifying the relationship between health care costs and independent variables, including age, gender, route of transmission and CD4 cell count at baseline, were developed.
RESULTS: Average annual health care costs were <euro>23,298 per patient from the societal perspective and <euro>19,103 from the statutory health insurance perspective. Most expenses are caused by antiretroviral medication (80 % of the total and 89 % of direct costs), while hospital costs represented 7 % of total expenditure. A statistically significant association was found between health care costs and clinical variables, with higher CD4 count and female gender generating lower costs, while increased antiretroviral experience and injection drug use led to higher expenditures (P < 0.05).
CONCLUSIONS: Expenditures for HIV-infection are driven mainly by drug costs. We identified several clinical variables influencing the costs of HIV-treatment. This information could assist policymakers when allocating limited health care resources to HIV care.

Entities:  

Mesh:

Year:  2012        PMID: 22990377     DOI: 10.1007/s10198-012-0425-4

Source DB:  PubMed          Journal:  Eur J Health Econ        ISSN: 1618-7598


  18 in total

1.  [Empirical standard costs for health economic evaluation in Germany -- a proposal by the working group methods in health economic evaluation].

Authors:  C Krauth; F Hessel; T Hansmeier; J Wasem; R Seitz; B Schweikert
Journal:  Gesundheitswesen       Date:  2005-10

Review 2.  Sex differences in antiretroviral therapy-associated intolerance and adverse events.

Authors:  Rebecca Clark
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

3.  [Appraisal of resource use in the German health-care system from the perspective of the statutory health insurance].

Authors:  S Braun; A Prenzler; T Mittendorf; J M von der Schulenburg
Journal:  Gesundheitswesen       Date:  2009-01-27

4.  Cost effectiveness of highly active antiretroviral therapy in HIV-infected patients. Swiss HIV Cohort Study.

Authors:  P P Sendi; H C Bucher; T Harr; B A Craig; M Schwietert; D Pfluger; A Gafni; M Battegay
Journal:  AIDS       Date:  1999-06-18       Impact factor: 4.177

5.  [Deficits in socioeconomic and psychosocial support of HIV-positive women].

Authors:  E Schulte; C Claes; T Körner; J M Graf von der Schulenburg; R E Schmidt; M Stoll
Journal:  Gesundheitswesen       Date:  2000-07

6.  Factors associated with HIV-infected women's delay in seeking medical care.

Authors:  V H Raveis; K Siegel; E Gorey
Journal:  AIDS Care       Date:  1998-10

7.  The changing direct costs of medical care for patients with HIV/AIDS, 1995-2001.

Authors:  Hartmut B Krentz; M Christopher Auld; M John Gill
Journal:  CMAJ       Date:  2003-07-22       Impact factor: 8.262

8.  Costs of intermittent versus continuous antiretroviral therapy in patients with controlled HIV infection: a substudy of the ANRS 106 Window Trial.

Authors:  Isabelle Charreau; Grégoire Jeanblanc; Philippe Tangre; Laurence Boyer; Marine Saouzanet; Bruno Marchou; Jean Michel Molina; Jean Pierre Aboulker; Isabelle Durand-Zaleski
Journal:  J Acquir Immune Defic Syndr       Date:  2008-12-01       Impact factor: 3.731

9.  The high cost of medical care for patients who present late (CD4 <200 cells/microL) with HIV infection.

Authors:  H B Krentz; M C Auld; M J Gill
Journal:  HIV Med       Date:  2004-03       Impact factor: 3.180

10.  Determinants of health care costs of HIV-positive patients in the Canary Islands, Spain.

Authors:  Juan Oliva-Moreno; Julio López-Bastida; Pedro Serrano-Aguilar; Lilisbeth Perestelo-Pérez
Journal:  Eur J Health Econ       Date:  2010-01-05
View more
  9 in total

1.  The prevalence of transmitted resistance to first-generation non-nucleoside reverse transcriptase inhibitors and its potential economic impact in HIV-infected patients.

Authors:  Sonya J Snedecor; Alexandra Khachatryan; Katherine Nedrow; Richard Chambers; Congyu Li; Seema Haider; Jennifer Stephens
Journal:  PLoS One       Date:  2013-08-22       Impact factor: 3.240

2.  Resource utilisation and cost of ambulatory HIV care in a regional HIV centre in Ireland: a micro-costing study.

Authors:  Aline Brennan; Arthur Jackson; Mary Horgan; Colm J Bergin; John P Browne
Journal:  BMC Health Serv Res       Date:  2015-04-03       Impact factor: 2.655

3.  Cost of HAART in Italy: multicentric evaluation and determinants from a large HIV outpatient cohort.

Authors:  Monica Tontodonati; Giovanni Cenderello; Benedetto Maurizio Celesia; Michele Trezzi; Tamara Ursini; Andrea Costantini; Domenico Marra; Ennio Polilli; Corrado Catalani; Luca Butini; Federica Sozio; Elena Mazzotta; Antonina Sciacca; Giuliano Rizzardini; Lamberto Manzoli; Alessandro Cozzi-Lepri; Giustino Parruti
Journal:  Clinicoecon Outcomes Res       Date:  2014-12-22

4.  Cost-effectiveness and budget effect of pre-exposure prophylaxis for HIV-1 prevention in Germany from 2018 to 2058.

Authors:  David A M C van de Vijver; Ann-Kathrin Richter; Charles A B Boucher; Barbara Gunsenheimer-Bartmeyer; Christian Kollan; Brooke E Nichols; Christoph D Spinner; Jürgen Wasem; Knud Schewe; Anja Neumann
Journal:  Euro Surveill       Date:  2019-02

5.  Cost-savings and potential cost-savings through the distribution of generic antiretroviral drugs within the statutory health insurance market of Germany between January 2017 and June 2019.

Authors:  Matthäus Lottes; Viviane Bremer; Christof Prugger; Christian Kollan; Daniel Schmidt
Journal:  BMC Health Serv Res       Date:  2022-01-13       Impact factor: 2.655

6.  Costs and mortality associated with HIV: a machine learning analysis of the French national health insurance database.

Authors:  Martin Prodel; Laurent Finkielsztejn; Laëtitia Roustand; Gaëlle Nachbaur; Lucie De Leotoing; Marie Genreau; Fabrice Bonnet; Jade Ghosn
Journal:  J Public Health Res       Date:  2021-11-29

7.  30 Years on Selected Issues in the Prevention of HIV among Persons Who Inject Drugs.

Authors:  D C Des Jarlais; S Pinkerton; H Hagan; V Guardino; J Feelemyer; H Cooper; A Hatzatkis; A Uuskula
Journal:  Adv Prev Med       Date:  2013-06-12

8.  Analysis of contemporary HIV/AIDS health care costs in Germany: Driving factors and distribution across antiretroviral therapy lines.

Authors:  Marina Treskova; Alexander Kuhlmann; Johannes Bogner; Martin Hower; Hans Heiken; Hans-Jürgen Stellbrink; Jörg Mahlich; Johann-Matthias Graf von der Schulenburg; Matthias Stoll
Journal:  Medicine (Baltimore)       Date:  2016-06       Impact factor: 1.889

9.  The burden of chronic diseases and cost-of-care in subjects with HIV infection in a Health District of Northern Italy over a 12-year period compared to that of the general population.

Authors:  Eugenia Quiros-Roldan; Michele Magoni; Elena Raffetti; Francesco Donato; Carmelo Scarcella; Giuseppe Paraninfo; Francesco Castelli
Journal:  BMC Public Health       Date:  2016-11-09       Impact factor: 3.295

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.