Literature DB >> 22989695

Synthetic cannabinoid intoxication: a case series and review.

Carson R Harris1, Ashley Brown.   

Abstract

BACKGROUND: Synthetic cannabinoid receptor agonists are becoming increasingly popular with adolescents as an abused substance. Chronic use of these drugs can lead to addiction syndrome and withdrawal symptoms similar to cannabis abuse. Due to their potential health risk, several countries have banned these substances.
OBJECTIVES: To report the clinical presentation and legislation status of synthetic cannabinoids in "Spice" products and alert the health care community about the identification and risk assessment problems of these compounds. CASE REPORTS: We retrospectively reviewed cases presenting to our Emergency Department (ED) during a 3-month period with chief complaints of Spice drug use before arrival. Six cases presented to our ED after using Spice drugs. Two patients were admitted after reporting seizures. All but one presented with tachycardia. Two patients had hallucinations. The average length of ED observation was 2.8 h. No patient with seizures had recurrent episodes.
CONCLUSION: Spice drugs can cause potentially serious health care conditions that necessitate ED evaluation. Most cases can be discharged from the ED after a period of observation. Legal issues surrounding these drugs are yet to be finalized in the United States.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22989695     DOI: 10.1016/j.jemermed.2012.07.061

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  58 in total

1.  High-resolution mass spectrometric determination of the synthetic cannabinoids MAM-2201, AM-2201, AM-2232, and their metabolites in postmortem plasma and urine by LC/Q-TOFMS.

Authors:  Kei Zaitsu; Hiroshi Nakayama; Mayumi Yamanaka; Kazuaki Hisatsune; Kentaro Taki; Tomomi Asano; Tooru Kamata; Munehiro Katagai; Yumi Hayashi; Maiko Kusano; Hitoshi Tsuchihashi; Akira Ishii
Journal:  Int J Legal Med       Date:  2015-09-08       Impact factor: 2.686

2.  K2--not the spice of life; synthetic cannabinoids and ST elevation myocardial infarction: a case report.

Authors:  Rita G McKeever; David Vearrier; Dorian Jacobs; Gregory LaSala; Jolene Okaneku; Michael I Greenberg
Journal:  J Med Toxicol       Date:  2015-03

Review 3.  Synthetic cannabinoids 2015: An update for pediatricians in clinical practice.

Authors:  Daniel Castellanos; Leonard M Gralnik
Journal:  World J Clin Pediatr       Date:  2016-02-08

Review 4.  The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products.

Authors:  Lisa K Brents; Paul L Prather
Journal:  Drug Metab Rev       Date:  2013-09-24       Impact factor: 4.518

5.  An outbreak of exposure to a novel synthetic cannabinoid.

Authors:  Andrew A Monte; Alvin C Bronstein; Dazhe J Cao; Kennon J Heard; Jason A Hoppe; Christopher O Hoyte; Janetta L Iwanicki; Eric J Lavonas
Journal:  N Engl J Med       Date:  2014-01-23       Impact factor: 91.245

Review 6.  Baths salts, spice, and related designer drugs: the science behind the headlines.

Authors:  Michael H Baumann; Ernesto Solis; Lucas R Watterson; Julie A Marusich; William E Fantegrossi; Jenny L Wiley
Journal:  J Neurosci       Date:  2014-11-12       Impact factor: 6.167

7.  New Nightmare "Synthetic Cannabinoids".

Authors:  Nurhan Fistikci
Journal:  Noro Psikiyatr Ars       Date:  2014-09-01       Impact factor: 1.339

Review 8.  Lower-Risk Cannabis Use Guidelines: A Comprehensive Update of Evidence and Recommendations.

Authors:  Benedikt Fischer; Cayley Russell; Pamela Sabioni; Wim van den Brink; Bernard Le Foll; Wayne Hall; Jürgen Rehm; Robin Room
Journal:  Am J Public Health       Date:  2017-06-23       Impact factor: 9.308

9.  Synthetic cannabinoid "Black Mamba" infidelity in patients presenting for emergency stabilization in Colorado: a P SCAN Cohort.

Authors:  Nicklaus Brandehoff; Axel Adams; Kyle McDaniel; Samuel D Banister; Roy Gerona; Andrew A Monte
Journal:  Clin Toxicol (Phila)       Date:  2017-09-01       Impact factor: 4.467

10.  Ischemic stroke after use of the synthetic marijuana "spice".

Authors:  Melissa J Freeman; David Z Rose; Martin A Myers; Clifton L Gooch; Andrea C Bozeman; W Scott Burgin
Journal:  Neurology       Date:  2013-11-08       Impact factor: 9.910

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