OBJECTIVE: To describe smoking and alcohol consumption trends in patients with oral cavity cancer over the past 25 years. DESIGN: Retrospective cohort study. SETTING: Single-institution tertiary care cancer center. PATIENTS: Patients with oral cancer treated primarily with surgery from 1985 to 2009. Patients with previous head and neck cancer were excluded. MAIN OUTCOME MEASURES: The medical records of 1617 patients were reviewed. Patient demographics and details on smoking and alcohol consumption were recorded. Patients were divided in 5 different cohorts according to the year of initial surgery. RESULTS: There were no differences in sex, age, or stage of disease among cohorts. Oral tongue was the most common subsite (49%). There was a progressive decrease in tobacco use; 80% in cohort 1 vs 60% in cohort 5 (P < .001). A decrease in the daily amount of tobacco used was also found; 55% of patients in cohort 1 smoked more than 1 pack per day compared with 30% in cohort 5 (P < .001). Alcohol consumption decreased from 80% in cohort 1 to 67% in cohort 5 (P < .007). The percentage of patients who consumed more than 3 drinks per day decreased from 23% in cohort 1 to 9% in cohort 5 (P < .001). CONCLUSION: Over the past 25 years there has been a progressive decrease in the prevalence of tobacco and alcohol users in patients with oral cancer.
OBJECTIVE: To describe smoking and alcohol consumption trends in patients with oral cavity cancer over the past 25 years. DESIGN: Retrospective cohort study. SETTING: Single-institution tertiary care cancer center. PATIENTS: Patients with oral cancer treated primarily with surgery from 1985 to 2009. Patients with previous head and neck cancer were excluded. MAIN OUTCOME MEASURES: The medical records of 1617 patients were reviewed. Patient demographics and details on smoking and alcohol consumption were recorded. Patients were divided in 5 different cohorts according to the year of initial surgery. RESULTS: There were no differences in sex, age, or stage of disease among cohorts. Oral tongue was the most common subsite (49%). There was a progressive decrease in tobacco use; 80% in cohort 1 vs 60% in cohort 5 (P < .001). A decrease in the daily amount of tobacco used was also found; 55% of patients in cohort 1 smoked more than 1 pack per day compared with 30% in cohort 5 (P < .001). Alcohol consumption decreased from 80% in cohort 1 to 67% in cohort 5 (P < .007). The percentage of patients who consumed more than 3 drinks per day decreased from 23% in cohort 1 to 9% in cohort 5 (P < .001). CONCLUSION: Over the past 25 years there has been a progressive decrease in the prevalence of tobacco and alcohol users in patients with oral cancer.
Authors: Daniella Karassawa Zanoni; Pablo H Montero; Jocelyn C Migliacci; Jatin P Shah; Richard J Wong; Ian Ganly; Snehal G Patel Journal: Oral Oncol Date: 2019-02-15 Impact factor: 5.337
Authors: Daniel S W Tan; Fui Teen Chong; Hui Sun Leong; Shen Yon Toh; Dawn P Lau; Xue Lin Kwang; Xiaoqian Zhang; Gopinath M Sundaram; Gek San Tan; Mei Mei Chang; Boon Tin Chua; Wan Teck Lim; Eng Huat Tan; Mei Kim Ang; Tony K H Lim; Prabha Sampath; Balram Chowbay; Anders J Skanderup; Ramanuj DasGupta; N Gopalakrishna Iyer Journal: Nat Med Date: 2017-09-18 Impact factor: 53.440
Authors: Andre Luiz Vettore; Kalpana Ramnarayanan; Gregory Poore; Kevin Lim; Choon Kiat Ong; Kie Kyon Huang; Hui Sun Leong; Fui Teen Chong; Tony Kiat-Hon Lim; Weng Khong Lim; Ioana Cutcutache; John R Mcpherson; Yuka Suzuki; Shenli Zhang; Thakshayeni Skanthakumar; Weining Wang; Daniel S W Tan; Byoung Chul Cho; Bin Tean Teh; Steve Rozen; Patrick Tan; N Gopalakrishna Iyer Journal: Genome Med Date: 2015-09-23 Impact factor: 11.117