Literature DB >> 22986552

Searching for the Holy Grail; protein-protein interaction analysis and modulation.

Xavier Morelli1, Ted Hupp.   

Abstract

The first EMBO workshop on 'Protein-Protein Interaction Analysis & Modulation' took place in June 2012 in Roscoff, France. It brought together researchers to discuss the growing field of protein network analysis and the modulation of protein-protein interactions, as well as outstanding related issues including the daunting challenge of integrating interactomes in systems biology and in the modelling of signalling networks.

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Year:  2012        PMID: 22986552      PMCID: PMC3463974          DOI: 10.1038/embor.2012.137

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


  6 in total

Review 1.  Motif switches: decision-making in cell regulation.

Authors:  Kim Van Roey; Toby J Gibson; Norman E Davey
Journal:  Curr Opin Struct Biol       Date:  2012-04-03       Impact factor: 6.809

Review 2.  WD40 proteins propel cellular networks.

Authors:  Christian U Stirnimann; Evangelia Petsalaki; Robert B Russell; Christoph W Müller
Journal:  Trends Biochem Sci       Date:  2010-05-05       Impact factor: 13.807

Review 3.  Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I).

Authors:  Xavier Morelli; Raphaël Bourgeas; Philippe Roche
Journal:  Curr Opin Chem Biol       Date:  2011-06-22       Impact factor: 8.822

Review 4.  Intrinsically unstructured proteins and their functions.

Authors:  H Jane Dyson; Peter E Wright
Journal:  Nat Rev Mol Cell Biol       Date:  2005-03       Impact factor: 94.444

5.  An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.

Authors:  Derek F Ceccarelli; Xiaojing Tang; Benoit Pelletier; Stephen Orlicky; Weilin Xie; Veronique Plantevin; Dante Neculai; Yang-Chieh Chou; Abiodun Ogunjimi; Abdallah Al-Hakim; Xaralabos Varelas; Joanna Koszela; Gregory A Wasney; Masoud Vedadi; Sirano Dhe-Paganon; Sarah Cox; Shuichan Xu; Antonia Lopez-Girona; Frank Mercurio; Jeff Wrana; Daniel Durocher; Sylvain Meloche; David R Webb; Mike Tyers; Frank Sicheri
Journal:  Cell       Date:  2011-06-16       Impact factor: 41.582

6.  ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Authors:  Shuhei Matsuoka; Bryan A Ballif; Agata Smogorzewska; E Robert McDonald; Kristen E Hurov; Ji Luo; Corey E Bakalarski; Zhenming Zhao; Nicole Solimini; Yaniv Lerenthal; Yosef Shiloh; Steven P Gygi; Stephen J Elledge
Journal:  Science       Date:  2007-05-25       Impact factor: 47.728

  6 in total
  5 in total

1.  Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein.

Authors:  Terry A Gray; Euan Murray; Matthew W Nowicki; Lucy Remnant; Alexander Scherl; Petr Muller; Borek Vojtesek; Ted R Hupp
Journal:  Protein Sci       Date:  2013-07-25       Impact factor: 6.725

2.  2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine.

Authors:  Véronique Hamon; Raphael Bourgeas; Pierre Ducrot; Isabelle Theret; Laura Xuereb; Marie Jeanne Basse; Jean Michel Brunel; Sebastien Combes; Xavier Morelli; Philippe Roche
Journal:  J R Soc Interface       Date:  2013-11-06       Impact factor: 4.118

3.  2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions.

Authors:  Marie-Jeanne Basse; Stéphane Betzi; Xavier Morelli; Philippe Roche
Journal:  Database (Oxford)       Date:  2016-03-15       Impact factor: 3.451

4.  PPIMpred: a web server for high-throughput screening of small molecules targeting protein-protein interaction.

Authors:  Tanmoy Jana; Abhirupa Ghosh; Sukhen Das Mandal; Raja Banerjee; Sudipto Saha
Journal:  R Soc Open Sci       Date:  2017-04-19       Impact factor: 2.963

5.  The Sequence-specific Peptide-binding Activity of the Protein Sulfide Isomerase AGR2 Directs Its Stable Binding to the Oncogenic Receptor EpCAM.

Authors:  M Aiman Mohtar; Lenka Hernychova; J Robert O'Neill; Melanie L Lawrence; Euan Murray; Borek Vojtesek; Ted R Hupp
Journal:  Mol Cell Proteomics       Date:  2018-01-16       Impact factor: 5.911

  5 in total

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