Literature DB >> 22986435

Disease mechanisms in MS: the potassium channel KIR4.1--a potential autoantigen in MS.

Michael K Racke1.   

Abstract

Multiple sclerosis is an inflammatory, demyelinating disease in which antigens of the myelin sheath have been considered the autoimmune target. A recent study suggests that the potassium channel KIR4.1 is another potential autoantigen in some patients with multiple sclerosis, and might also be a target in other demyelinating diseases.

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Year:  2012        PMID： 22986435     DOI： 10.1038/nrneurol.2012.193

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN： 1759-4758            Impact factor:   42.937


  8 in total

1.  Evidence-based guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Authors:  T F Scott; E M Frohman; J De Seze; G S Gronseth; B G Weinshenker
Journal:  Neurology       Date:  2011-12-07       Impact factor: 9.910

Review 2.  Multiple sclerosis--the plaque and its pathogenesis.

Authors:  Elliot M Frohman; Michael K Racke; Cedric S Raine
Journal:  N Engl J Med       Date:  2006-03-02       Impact factor: 91.245

3.  Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes.

Authors:  Shannon R Hinson; Michael F Romero; Bogdan F Gh Popescu; Claudia F Lucchinetti; James P Fryer; Hartwig Wolburg; Petra Fallier-Becker; Susan Noell; Vanda A Lennon
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-29       Impact factor: 11.205

4.  Potassium channel KIR4.1 as an immune target in multiple sclerosis.

Authors:  Rajneesh Srivastava; Muhammad Aslam; Sudhakar Reddy Kalluri; Lucas Schirmer; Dorothea Buck; Björn Tackenberg; Veit Rothhammer; Andrew Chan; Ralf Gold; Achim Berthele; Jeffrey L Bennett; Thomas Korn; Bernhard Hemmer
Journal:  N Engl J Med       Date:  2012-07-12       Impact factor: 91.245

5.  Immunocytochemical studies of aquaporin 4, Kir4.1, and α1-syntrophin in the astrocyte endfeet of mouse brain capillaries.

Authors:  Hisatsugu Masaki; Yoshihiro Wakayama; Hajime Hara; Takahiro Jimi; Akihiko Unaki; Shoji Iijima; Hiroaki Oniki; Kiyoko Nakano; Koji Kishimoto; Yoshiko Hirayama
Journal:  Acta Histochem Cytochem       Date:  2010-07-21       Impact factor: 1.938

6.  Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis.

Authors:  Shanu F Roemer; Joseph E Parisi; Vanda A Lennon; Eduardo E Benarroch; Hans Lassmann; Wolfgang Bruck; Raul N Mandler; Brian G Weinshenker; Sean J Pittock; Dean M Wingerchuk; Claudia F Lucchinetti
Journal:  Brain       Date:  2007-02-04       Impact factor: 13.501

7.  B-cell depletion with rituximab in relapsing-remitting multiple sclerosis.

Authors:  Stephen L Hauser; Emmanuelle Waubant; Douglas L Arnold; Timothy Vollmer; Jack Antel; Robert J Fox; Amit Bar-Or; Michael Panzara; Neena Sarkar; Sunil Agarwal; Annette Langer-Gould; Craig H Smith
Journal:  N Engl J Med       Date:  2008-02-14       Impact factor: 91.245

8.  IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel.

Authors:  Vanda A Lennon; Thomas J Kryzer; Sean J Pittock; A S Verkman; Shannon R Hinson
Journal:  J Exp Med       Date:  2005-08-08       Impact factor: 14.307
  8 in total
  2 in total

Review 1.  The afferent visual pathway: designing a structural-functional paradigm of multiple sclerosis.

Authors:  Fiona Costello
Journal:  ISRN Neurol       Date:  2013-11-06

2.  Absence of antibodies against KIR4.1 in multiple sclerosis: A three-technique approach and systematic review.

Authors:  Miquel Navas-Madroñal; Ana Valero-Mut; María José Martínez-Zapata; Manuel Javier Simón-Talero; Sebastián Figueroa; Nuria Vidal-Fernández; Mariana López-Góngora; Antonio Escartín; Luis Querol
Journal:  PLoS One       Date:  2017-04-17       Impact factor: 3.240
  2 in total

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