BACKGROUND AND OBJECTIVE: The coexistence of chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) increases with age. The occurrence, prognosis and therapeutic implications of concurrent COPD in elderly patients with CHF were investigated. METHODS: One hundred and eighteen consecutive patients, ≥ 65 years old with ≥ 10 pack/years of smoking and with a verified diagnosis of CHF in stable condition, were enrolled. They were followed for a mean of 1029 (range 758-1064) days. All patients had spirometry and the diagnosis and classification of COPD were made according to Global Initiative for Chronic Obstructive Lung Disease guidelines. RESULTS: The mean occurrence of COPD was 30% (90% confidence interval: 24-37%). At baseline in patients with CHF and COPD, there was a shorter 6-min walk distance, lower arterial oxygen tension, glomerular filtration rate and higher N-terminal pro-B-type natriuretic peptide (all P < 0.05). The prescription of CHF therapies, including β-blockers, was similar in the two groups. After follow up, the presence of COPD in patients with CHF did not appear to influence survival. CONCLUSIONS: COPD is relatively frequent in elderly patients with CHF. COPD did not alter survival.
BACKGROUND AND OBJECTIVE: The coexistence of chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) increases with age. The occurrence, prognosis and therapeutic implications of concurrent COPD in elderly patients with CHF were investigated. METHODS: One hundred and eighteen consecutive patients, ≥ 65 years old with ≥ 10 pack/years of smoking and with a verified diagnosis of CHF in stable condition, were enrolled. They were followed for a mean of 1029 (range 758-1064) days. All patients had spirometry and the diagnosis and classification of COPD were made according to Global Initiative for Chronic Obstructive Lung Disease guidelines. RESULTS: The mean occurrence of COPD was 30% (90% confidence interval: 24-37%). At baseline in patients with CHF and COPD, there was a shorter 6-min walk distance, lower arterial oxygen tension, glomerular filtration rate and higher N-terminal pro-B-type natriuretic peptide (all P < 0.05). The prescription of CHF therapies, including β-blockers, was similar in the two groups. After follow up, the presence of COPD in patients with CHF did not appear to influence survival. CONCLUSIONS:COPD is relatively frequent in elderly patients with CHF. COPD did not alter survival.
Authors: Mark J Valk; Berna D Broekhuizen; Arend Mosterd; Nicolaas P Zuithoff; Arno W Hoes; Frans H Rutten Journal: Int J Chron Obstruct Pulmon Dis Date: 2015-06-26
Authors: S Bektas; F M E Franssen; V van Empel; N Uszko-Lencer; J Boyne; C Knackstedt; H P Brunner-La Rocca Journal: Neth Heart J Date: 2017-05 Impact factor: 2.380
Authors: Armine G Minasian; Frank Jj van den Elshout; Pn Richard Dekhuijzen; Petra Je Vos; Frank F Willems; Paul Jpc van den Bergh; Yvonne F Heijdra Journal: Transl Respir Med Date: 2014-09-25
Authors: Eleanor L Axson; Varun Sundaram; Chloe I Bloom; Alex Bottle; Martin R Cowie; Jennifer K Quint Journal: BMJ Open Date: 2018-06-30 Impact factor: 2.692