INTRODUCTION: This study reports the first cases of neurogenic stunned myocardium in two children with vein of Galen aneurysmal malformation after interventional treatment. PATIENTS: Two newborns with vein of Galen aneurysmal malformation and high output cardiac failure developed a severe reversible left ventricular dysfunction shortly after embolization, concurrently with acute hydrocephalus. RESULTS: There was a resolution of the cardiac symptoms of left ventricular dysfunction within a few days under treatment with milrinone and dobutamine. CONCLUSIONS: Reversible left ventricular dysfunction is observed in adult patients mainly after subarachnoid hemorrhage and is called neurogenic stunned myocardium (NSM). Other forms of brain injuries have also been identified accounting for this condition in adults. In pediatric population especially with specific cerebral diseases, NSM may be underdiagnosed.
INTRODUCTION: This study reports the first cases of neurogenic stunned myocardium in two children with vein of Galen aneurysmal malformation after interventional treatment. PATIENTS: Two newborns with vein of Galen aneurysmal malformation and high output cardiac failure developed a severe reversible left ventricular dysfunction shortly after embolization, concurrently with acute hydrocephalus. RESULTS: There was a resolution of the cardiac symptoms of left ventricular dysfunction within a few days under treatment with milrinone and dobutamine. CONCLUSIONS: Reversible left ventricular dysfunction is observed in adult patients mainly after subarachnoid hemorrhage and is called neurogenic stunned myocardium (NSM). Other forms of brain injuries have also been identified accounting for this condition in adults. In pediatric population especially with specific cerebral diseases, NSM may be underdiagnosed.
Authors: Gregory G Heuer; Brandon Gabel; Lauren A Beslow; Michael F Stiefel; Erin S Schwartz; Phillip B Storm; Rebecca N Ichord; Robert W Hurst Journal: Childs Nerv Syst Date: 2010-01-05 Impact factor: 1.475
Authors: L Chevret; P Durand; H Alvarez; V Lambert; L Caeymax; G Rodesch; D Devictor; P Lasjaunias Journal: Intensive Care Med Date: 2002-07-05 Impact factor: 17.440