Literature DB >> 22982567

Cytosolic lipid inclusions formed during infection by viral and bacterial pathogens.

Matthias Stehr1, Ayssar A Elamin, Mahavir Singh.   

Abstract

Lipid inclusions play an important role in several pathological processes. Intracellular bacterial pathogens, such as members of the Mycobacterium and Chlamydia species are able to trigger the formation of lipid-laden foamy macrophages. Lipid droplet accumulation in the host constitutes a reservoir used by the bacilli for long-term persistence. Viruses need lipid droplets as assembly platform. We present the current knowledge about structural, functional and regulatory aspects of lipid inclusions.
Copyright © 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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Year:  2012        PMID： 22982567     DOI： 10.1016/j.micinf.2012.08.001

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  10 in total

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  10 in total

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