Literature DB >> 22982303

Biomarkers of Parkinson's disease: current status and future perspectives.

Jian Wang1, Jake G Hoekstra, Chuantao Zuo, Travis J Cook, Jing Zhang.   

Abstract

This review summarizes major advances in biomarker discovery for diagnosis, differential diagnosis and progression of Parkinson's disease (PD), with emphasis on neuroimaging and biochemical markers. Potential strategies to develop biomarkers capable of predicting PD in the prodromal stage before the appearance of motor symptoms or correlating with nonmotor symptoms, an active area of research, are also discussed.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22982303      PMCID： PMC3557745          DOI： 10.1016/j.drudis.2012.09.001

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  87 in total

1.  Plasma levels of DJ-1 as a possible marker for progression of sporadic Parkinson's disease.

Authors:  Masaaki Waragai; Masaaki Nakai; Jianshe Wei; Masayo Fujita; Hideya Mizuno; Gilbert Ho; Eliezer Masliah; Hiroyasu Akatsu; Fusako Yokochi; Makoto Hashimoto
Journal:  Neurosci Lett       Date:  2007-08-11       Impact factor: 3.046

2.  18F-FP-CIT PET imaging and SPM analysis of dopamine transporters in Parkinson's disease in various Hoehn & Yahr stages.

Authors:  Jian Wang; Cuan-Tao Zuo; Yu-Ping Jiang; Yi-Hui Guan; Zheng-Ping Chen; Jing-De Xiang; Li-Qin Yang; Zheng-Tong Ding; Jian-Jun Wu; Hui-Lin Su
Journal:  J Neurol       Date:  2007-03-02       Impact factor: 4.849

3.  CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases.

Authors:  Jing Zhang; Izabela Sokal; Elaine R Peskind; Joseph F Quinn; Joseph Jankovic; Christopher Kenney; Kathryn A Chung; Steven P Millard; John G Nutt; Thomas J Montine
Journal:  Am J Clin Pathol       Date:  2008-04       Impact factor: 2.493

4.  Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.

Authors:  Daniel G Healy; Mario Falchi; Sean S O'Sullivan; Vincenzo Bonifati; Alexandra Durr; Susan Bressman; Alexis Brice; Jan Aasly; Cyrus P Zabetian; Stefano Goldwurm; Joaquim J Ferreira; Eduardo Tolosa; Denise M Kay; Christine Klein; David R Williams; Connie Marras; Anthony E Lang; Zbigniew K Wszolek; Jose Berciano; Anthony H V Schapira; Timothy Lynch; Kailash P Bhatia; Thomas Gasser; Andrew J Lees; Nicholas W Wood
Journal:  Lancet Neurol       Date:  2008-06-06       Impact factor: 44.182

5.  Midbrain iron content in early Parkinson disease: a potential biomarker of disease status.

Authors:  W R Wayne Martin; Marguerite Wieler; Myrlene Gee
Journal:  Neurology       Date:  2008-01-02       Impact factor: 9.910

6.  Case control study of diffusion tensor imaging in Parkinson's disease.

Authors:  L-L Chan; H Rumpel; K Yap; E Lee; H-V Loo; G-L Ho; S Fook-Chong; Y Yuen; E-K Tan
Journal:  J Neurol Neurosurg Psychiatry       Date:  2007-07-05       Impact factor: 10.154

7.  Metabolomic profiling to develop blood biomarkers for Parkinson's disease.

Authors:  Mikhail Bogdanov; Wayne R Matson; Lei Wang; Theodore Matson; Rachel Saunders-Pullman; Susan S Bressman; M Flint Beal
Journal:  Brain       Date:  2008-02       Impact factor: 13.501

8.  alpha-Synuclein gene duplication is present in sporadic Parkinson disease.

Authors:  T-B Ahn; S Y Kim; J Y Kim; S-S Park; D S Lee; H J Min; Y K Kim; S E Kim; J-M Kim; H-J Kim; J Cho; B S Jeon
Journal:  Neurology       Date:  2007-07-11       Impact factor: 9.910

9.  Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease.

Authors:  Andrew Feigin; Michael G Kaplitt; Chengke Tang; Tanya Lin; Paul Mattis; Vijay Dhawan; Matthew J During; David Eidelberg
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-27       Impact factor: 11.205

10.  The specificity and sensitivity of transcranial ultrasound in the differential diagnosis of Parkinson's disease: a prospective blinded study.

Authors:  Alexandra Gaenslen; Barbara Unmuth; Jana Godau; Inga Liepelt; Adriana Di Santo; Katherine Johanna Schweitzer; Thomas Gasser; Hans-Jürgen Machulla; Matthias Reimold; Kenneth Marek; Daniela Berg
Journal:  Lancet Neurol       Date:  2008-04-03       Impact factor: 44.182
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  16 in total

1.  Clinical utility of visualisation of nigrosome-1 in patients with Parkinson's disease.

Authors:  Albert Stezin; Rajini M Naduthota; Ragasudha Botta; Shriram Varadharajan; Abhishek Lenka; Jitender Saini; Ravi Yadav; Pramod Kumar Pal
Journal:  Eur Radiol       Date:  2017-08-04       Impact factor: 5.315

Review 2.  Unbiased approaches to biomarker discovery in neurodegenerative diseases.

Authors:  Alice S Chen-Plotkin
Journal:  Neuron       Date:  2014-11-05       Impact factor: 17.173

3.  Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity.

Authors:  Chen Ran; Yanwu Yang; Chenfei Ye; Haiyan Lv; Ting Ma
Journal:  Hum Brain Mapp       Date:  2022-09-12       Impact factor: 5.399

Review 4.  Region-Specific Iron Measured by MRI as a Biomarker for Parkinson's Disease.

Authors:  Xiaojun Guan; Xiaojun Xu; Minming Zhang
Journal:  Neurosci Bull       Date:  2017-05-17       Impact factor: 5.203

Review 5.  Longitudinal Progression Markers of Parkinson's Disease: Current View on Structural Imaging.

Authors:  Jing Yang; Roxana G Burciu; David E Vaillancourt
Journal:  Curr Neurol Neurosci Rep       Date:  2018-10-02       Impact factor: 5.081

6.  Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson's model.

Authors:  Tanya Chotibut; Richard W Davis; Jennifer C Arnold; Zachary Frenchek; Shawn Gurwara; Vimala Bondada; James W Geddes; Michael F Salvatore
Journal:  Mol Neurobiol       Date:  2013-12-03       Impact factor: 5.590

Review 7.  Alpha-Synuclein as a Biomarker for Parkinson's Disease.

Authors:  Anzari Atik; Tessandra Stewart; Jing Zhang
Journal:  Brain Pathol       Date:  2016-05       Impact factor: 6.508

8.  DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease.

Authors:  Xiangmin Lin; Travis J Cook; Cyrus P Zabetian; James B Leverenz; Elaine R Peskind; Shu-Ching Hu; Kevin C Cain; Catherine Pan; John Scott Edgar; David R Goodlett; Brad A Racette; Harvey Checkoway; Thomas J Montine; Min Shi; Jing Zhang
Journal:  Sci Rep       Date:  2012-12-11       Impact factor: 4.379

9.  The 'swallow tail' appearance of the healthy nigrosome - a new accurate test of Parkinson's disease: a case-control and retrospective cross-sectional MRI study at 3T.

Authors:  Stefan T Schwarz; Mohammed Afzal; Paul S Morgan; Nin Bajaj; Penny A Gowland; Dorothee P Auer
Journal:  PLoS One       Date:  2014-04-07       Impact factor: 3.240

10.  Mini Review: linkages between essential tremor and Parkinson's disease?

Authors:  Yiwen Wu; Jianqing Ding; Yuan Gao; Shangdi Chen; Li Li; Rena Li
Journal:  Front Cell Neurosci       Date:  2013-07-31       Impact factor: 5.505
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