| Literature DB >> 22980833 |
Ming Ye1, Yan Wang, Geng-yi Guo, Yun-long He, Ying Lu, Ying-wang Ye, Qing-hua Yang, Pei-zhou Yang.
Abstract
Seven kinds of amino acids were used to modify the non-water-soluble extracellular melanin (LEM346) from Lachnum YM-346. It was found that arginine-melanin (ALEM346) had the highest solubility, being 4.55% (gg(-1)) in 30°C distilled water. Elemental analysis, infrared spectrum and mass spectrum analysis revealed that LEM346 molecule contained indole quinone structure, its molecular formula speculated to be C(18)H(8)O(6)N(2). Infrared spectrum analysis showed that ALEM346 had characteristic absorption peaks at 1672.346 and 1637.679 cm(-1). Mass spectrum analysis indicated that ALEM346 contained three types of arginine-melanin molecules. When the ALEM346 concentration was 500 mgL(-1), its total antioxidant capacity was equivalent to α-tocopherol of 46.65 mmolL(-1), the DPPH() and O(2)(-) scavenging rates and the Fe(2+) chelating rate were 89.05%, 93.81% and 80.18%, respectively, suggesting that the antioxidant activity of ALEM346 was stronger than that of LEM346.Entities:
Mesh：
Substances：
Year: 2012 PMID： 22980833 DOI： 10.1016/j.foodchem.2012.06.120
Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514