Literature DB >> 22978698

One-pot synthesis of amides from aldehydes and amines via C-H bond activation.

Roberta Cadoni1, Andrea Porcheddu, Giampaolo Giacomelli, Lidia De Luca.   

Abstract

A one-pot synthesis of amides from aldheydes with N-chloroamines, prepared in situ from amines, has been developed. Both aliphatic and aromatic aldehydes and many types of mono- and disubstituted amines are tolerant in this transformation. This cross-coupling reaction appears simple and convenient, has a wide substrate scope and makes use of cheap, abundant, and easily available reagents.

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Year:  2012        PMID： 22978698     DOI： 10.1021/ol302175v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Visible-Light Photoredox-Catalyzed Amidation of Benzylic Alcohols.

Authors:  Silvia Gaspa; Andrea Farina; Mariella Tilocca; Andrea Porcheddu; Luisa Pisano; Massimo Carraro; Ugo Azzena; Lidia De Luca
Journal:  J Org Chem       Date:  2020-07-23       Impact factor: 4.354

2.  Direct synthesis of amides and imines by dehydrogenative homo or cross-coupling of amines and alcohols catalyzed by Cu-MOF.

Authors:  Soheil Zamani Anbardan; Javad Mokhtari; Ahmad Yari; Abolfazl Hassani Bozcheloei
Journal:  RSC Adv       Date:  2021-06-10       Impact factor: 4.036

3.  One-pot synthesis of amides via the oxidative amidation of aldehydes and amines catalyzed by a copper-MOF.

Authors:  Samira Jamalifard; Javad Mokhtari; Zohreh Mirjafary
Journal:  RSC Adv       Date:  2019-07-23       Impact factor: 4.036

4.  A general and atom-efficient continuous-flow approach to prepare amines, amides and imines via reactive N-chloramines.

Authors:  Katherine E Jolley; Michael R Chapman; A John Blacker
Journal:  Beilstein J Org Chem       Date:  2018-08-24       Impact factor: 2.883
  4 in total

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