Literature DB >> 2297748

Radioimmunodetection in rhabdo- and leiomyosarcoma with 111In-anti-myosin monoclonal antibody complex.

A Planting1, J Verweij, P Cox, M Pillay, G Stoter.   

Abstract

In patients with rhabdo- and leiomyosarcoma a radioimmunodiagnostic study was performed with 111In labeled F(ab) fragments of a monoclonal antibody against myosin. Eight patients with rhabdomyosarcoma and 18 patients with leiomyosarcoma were studied. Scanning was performed at 4, 24, and 48 h after administration of 74 MBeq of the antibody complex. A high uptake with a tumor:background ratio of 10:1 was observed in several patients with rhabdomyosarcoma but the results were less accurate in leiomyosarcoma.

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Year:  1990        PMID: 2297748

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  2 in total

Review 1.  Cardiac myofibrillar proteins: biochemical markers to estimate myocardial injury.

Authors:  K H Haider; W H Stimson
Journal:  Mol Cell Biochem       Date:  1999-04       Impact factor: 3.396

2.  Antimyosin scintigraphy in patients with acquired and hereditary muscular disorders.

Authors:  M Löfberg; K Liewendahl; S Savolainen; P Nikkinen; A Lamminen; E Tiula; H Somer
Journal:  Eur J Nucl Med       Date:  1994-10
  2 in total

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