Literature DB >> 22976335

Synthesis of marine diterpene isocyanide (-)-kalihinol Y and diterpene isothiocyanate (-)-10-epi-kalihinol I.

Hiroaki Miyaoka1, Yasunori Abe, Etsuko Kawashima.   

Abstract

The authors described the first synthesis of diterpene isocyanide (-)-kalihinol Y and diterpene isothiocyanate (-)-10-epi-kalihinol I from synthetic intermediates of kalihinol A. The absolute structures of these compounds were confirmed by these syntheses.

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Year:  2012        PMID： 22976335     DOI： 10.1248/cpb.c12-00485

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  4 in total

1.  Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold.

Authors:  Edward Avilés; Jacques Prudhomme; Karine G Le Roch; Scott G Franzblau; Kevin Chandrasena; Alejandro M S Mayer; Abimael D Rodríguez
Journal:  Bioorg Med Chem Lett       Date:  2015-09-15       Impact factor: 2.823

2.  Stereocontrolled Synthesis of Kalihinol C.

Authors:  Christopher A Reiher; Ryan A Shenvi
Journal:  J Am Chem Soc       Date:  2017-03-02       Impact factor: 15.419

3.  Concise Synthesis of the Antiplasmodial Isocyanoterpene 7,20-Diisocyanoadociane.

Authors:  Alexander S Karns; Bryan D Ellis; Philipp C Roosen; Zeinab Chahine; Karine G Le Roch; Christopher D Vanderwal
Journal:  Angew Chem Int Ed Engl       Date:  2019-08-27       Impact factor: 15.336

4.  Synthesis and potent antimalarial activity of kalihinol B.

Authors:  Mary Elisabeth Daub; Jacques Prudhomme; Karine Le Roch; Christopher D Vanderwal
Journal:  J Am Chem Soc       Date:  2015-04-09       Impact factor: 15.419
  4 in total

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