BACKGROUND: Few data exist on the serologic outcome of treponemal tests in congenital syphilis. METHODS: A chart review was conducted on all confirmed early congenital syphilis cases in Edmonton, Canada, from 2005-2010. RESULTS: Of the 16 cases identified, 11 (69%) infants seroreverted their treponemal tests by 18 months. Cases that did not serorevert their treponemal tests were statistically more likely to have delayed treatment and to have higher maternal rapid plasma reagin titers at birth. CONCLUSIONS: Our data suggest that the majority of early congenital syphilis cases will serorevert their treponemal tests by 18 months.
BACKGROUND: Few data exist on the serologic outcome of treponemal tests in congenital syphilis. METHODS: A chart review was conducted on all confirmed early congenital syphilis cases in Edmonton, Canada, from 2005-2010. RESULTS: Of the 16 cases identified, 11 (69%) infants seroreverted their treponemal tests by 18 months. Cases that did not serorevert their treponemal tests were statistically more likely to have delayed treatment and to have higher maternal rapid plasma reagin titers at birth. CONCLUSIONS: Our data suggest that the majority of early congenital syphilis cases will serorevert their treponemal tests by 18 months.
Authors: Pâmela Cristina Gaspar; Álisson Bigolin; José Boullosa Alonso Neto; Esdras Daniel Dos Santos Pereira; Maria Luiza Bazzo Journal: Rev Soc Bras Med Trop Date: 2021-05-17 Impact factor: 1.581
Authors: Ameeta E Singh; Paul N Levett; Kevin Fonseca; Gayatri C Jayaraman; Bonita E Lee Journal: Can J Infect Dis Med Microbiol Date: 2015 Jan-Feb Impact factor: 2.471
Authors: Elena Sulleiro; Marie Antoinette Frick; Carlota Rodó; Mateu Espasa; Claire Thorne; María Espiau; Andrea Martín-Nalda; Anna Suy; Carlo Giaquinto; Susana Melendo; Ariadna Rando; Ana Alarcón; Federico Martinón-Torres; Tomás Pumarola; Pere Soler-Palacín; Antoni Soriano-Arandes Journal: Medicine (Baltimore) Date: 2019-05 Impact factor: 1.817