Literature DB >> 22975320

A ubiquitin-binding rhomboid protease aimed at ERADication.

Yien Che Tsai1, Allan M Weissman.   

Abstract

Proteins are degraded from the ER by endoplasmic reticulum-associated degradation (ERAD). In a recent issue of Molecular Cell, Fleig et al. (2012) describe a role for a ubiquitin-binding rhomboid protease, RHBDL4, in degradation of select ERAD substrates. These findings and the significance of rhomboids and other intramembrane proteases are discussed.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22975320      PMCID： PMC3515669          DOI： 10.1016/j.devcel.2012.08.015

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  9 in total

Review 1.  Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans.

Authors:  M S Brown; J Ye; R B Rawson; J L Goldstein
Journal:  Cell       Date:  2000-02-18       Impact factor: 41.582

Review 2.  Intramembrane proteolysis in regulated protein trafficking.

Authors:  Marius K Lemberg
Journal:  Traffic       Date:  2011-06-13       Impact factor: 6.215

3.  Signal peptide peptidase is required for dislocation from the endoplasmic reticulum.

Authors:  Joana Loureiro; Brendan N Lilley; Eric Spooner; Vanessa Noriega; Domenico Tortorella; Hidde L Ploegh
Journal:  Nature       Date:  2006-05-31       Impact factor: 49.962

4.  Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins.

Authors:  Lina Fleig; Nina Bergbold; Priyanka Sahasrabudhe; Beate Geiger; Lejla Kaltak; Marius K Lemberg
Journal:  Mol Cell       Date:  2012-07-12       Impact factor: 17.970

5.  Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.

Authors:  Colin Adrain; Markus Zettl; Yonka Christova; Neil Taylor; Matthew Freeman
Journal:  Science       Date:  2012-01-13       Impact factor: 47.728

6.  Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum.

Authors:  Ethan J Greenblatt; James A Olzmann; Ron R Kopito
Journal:  Nat Struct Mol Biol       Date:  2011-09-11       Impact factor: 15.369

7.  The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and Cancer.

Authors:  Yien Che Tsai; Allan M Weissman
Journal:  Genes Cancer       Date:  2010-07-01

8.  Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.

Authors:  Sara Cipolat; Tomasz Rudka; Dieter Hartmann; Veronica Costa; Lutgarde Serneels; Katleen Craessaerts; Kristine Metzger; Christian Frezza; Wim Annaert; Luciano D'Adamio; Carmen Derks; Tim Dejaegere; Luca Pellegrini; Rudi D'Hooge; Luca Scorrano; Bart De Strooper
Journal:  Cell       Date:  2006-07-14       Impact factor: 41.582

9.  Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling.

Authors:  Markus Zettl; Colin Adrain; Kvido Strisovsky; Viorica Lastun; Matthew Freeman
Journal:  Cell       Date:  2011-04-01       Impact factor: 41.582
  9 in total
  2 in total

Review 1.  The role of rhomboid superfamily members in protein homeostasis: Mechanistic insight and physiological implications.

Authors:  Rachel R Kandel; Sonya E Neal
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2020-07-06       Impact factor: 5.011

Review 2.  ERAD and how viruses exploit it.

Authors:  Hyewon Byun; Yongqiang Gou; Adam Zook; Mary M Lozano; Jaquelin P Dudley
Journal:  Front Microbiol       Date:  2014-07-03       Impact factor: 5.640
  2 in total

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