Literature DB >> 22973988

Spontaneous clostridial myonecrosis after pregnancy - emergency treatment to the limb salvage and functional recovery: a case report.

Barbara De Angelis1, Paolo Cerulli, Lucarini Lucilla, Augusto Fusco, Camilla Di Pasquali, Ilaria Bocchini, Fabrizio Orlandi, Annarita Agovino, Valerio Cervelli.   

Abstract

Clostridial myonecrosis (CM) is a rare, life threatening necrotizing infection of a skeletal muscle caused by Clostridium perfringens in the majority of cases. The diagnosis may be difficult because of few diagnostic and cutaneous signs early in its course. Standard therapy involves surgical debridements of a devitalized tissue and high-dose organism-specific antibiotic therapy. The hyperbaric oxygen has also showed its usefulness in the treatment of these infections. Autograft systems as tissue replacement, based on bioengineered materials, have been demonstrated to be safe and effective treatments for chronic wounds and a suitable physiotherapy is recommended for the recovery of functional impairments of upper extremities. We present a rare case of CM of right upper limb treated with a combination of standard treatments and new techniques.
© 2012 The Authors. International Wound Journal © 2012 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  Clostridium perfringens; Myonecrosis; Rehabilitation; Tissue regeneration

Mesh:

Substances:

Year:  2012        PMID: 22973988      PMCID: PMC7950850          DOI: 10.1111/j.1742-481X.2012.01072.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  15 in total

1.  Hyperbaric oxygen therapy for necrotizing fasciitis reduces mortality and the need for debridements.

Authors:  J A Riseman; W A Zamboni; A Curtis; D R Graham; H R Konrad; D S Ross
Journal:  Surgery       Date:  1990-11       Impact factor: 3.982

2.  More on clostridial myonecrosis.

Authors:  T T Levins
Journal:  J Emerg Nurs       Date:  1997-02       Impact factor: 1.836

Review 3.  Necrotizing soft tissue infections.

Authors:  J D Urschel
Journal:  Postgrad Med J       Date:  1999-11       Impact factor: 2.401

4.  Skin grafts as pharmacological agents: pre-wounding of the donor site.

Authors:  R S Kirsner; V Falanga; F A Kerdel; M H Katz; W H Eaglstein
Journal:  Br J Dermatol       Date:  1996-08       Impact factor: 9.302

Review 5.  Necrotizing soft-tissue infections.

Authors:  M E Sutherland; A A Meyer
Journal:  Surg Clin North Am       Date:  1994-06       Impact factor: 2.741

6.  Spontaneous clostridial myonecrosis with abdominal involvement in a nonimmunocompromised patient.

Authors:  R S Rich; R F Salluzzo
Journal:  Ann Emerg Med       Date:  1993-09       Impact factor: 5.721

7.  Effects of hyperbaric oxygen on procollagen messenger RNA levels and collagen synthesis in the healing of rat tendon laceration.

Authors:  Y Ishii; Y Miyanaga; H Shimojo; T Ushida; T Tateishi
Journal:  Tissue Eng       Date:  1999-06

8.  Fulminant massive gas gangrene caused by Clostridium perfringens.

Authors:  Shoji Kuroda; Yumi Okada; Masaki Mita; Yasuo Okamoto; Hirotaka Kato; Shigemitsu Ueyama; Ikuzo Fujii; Sumiharu Morita; Yasuaki Yoshida
Journal:  Intern Med       Date:  2005-05       Impact factor: 1.271

9.  Beneficial actions of exogenous hyaluronic acid on wound healing.

Authors:  S R King; W L Hickerson; K G Proctor
Journal:  Surgery       Date:  1991-01       Impact factor: 3.982

10.  Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality.

Authors:  Chin-Ho Wong; Haw-Chong Chang; Shanker Pasupathy; Lay-Wai Khin; Jee-Lim Tan; Cheng-Ooi Low
Journal:  J Bone Joint Surg Am       Date:  2003-08       Impact factor: 5.284

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