Literature DB >> 22973971

B-(3,3-difluoroallyl)diisopinocampheylborane for the enantioselective fluoroallylboration of aldehydes.

P Veeraraghavan Ramachandran1, Agnieszka Tafelska-Kaczmarek, Anamitra Chatterjee.   

Abstract

The fluoroallylboration of aldehydes with B-(3,3-difluoroallyl)diisopinocampheylborane, which was prepared via the hydroboration of 1,1-difluoroallene, provides chiral 2,2-gem-difluorinated homoallylic alcohols in good yields and 91-97% ee.

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Year:  2012        PMID: 22973971     DOI: 10.1021/jo300970z

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

Review 1.  Recent Advances in the Construction of Fluorinated Organoboron Compounds.

Authors:  Xingxing Ma; Zhijie Kuang; Qiuling Song
Journal:  JACS Au       Date:  2021-12-30
  1 in total

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