| Literature DB >> 22971930 |
Celine de Esch1, Roderick Slieker, André Wolterbeek, Ruud Woutersen, Didima de Groot.
Abstract
The zebrafish is a powerful toxicity model; biochemical assays can be combined with observations at a structural and functional level within one individual. This mini review summarises the potency of zebrafish as a model for developmental neurotoxicity screening, and its possibilities to investigate working mechanisms of toxicants. The use of zebrafish in toxicity research can ultimately lead to the refinement or reduction of animal use.Entities:
Mesh:
Year: 2012 PMID: 22971930 DOI: 10.1016/j.ntt.2012.08.006
Source DB: PubMed Journal: Neurotoxicol Teratol ISSN: 0892-0362 Impact factor: 3.763