Literature DB >> 22971448

A contemporary approach to the obstetric management of women with heart disease.

Julie E Robertson1, Candice K Silversides2, May Ling Mah2, Julia Kulikowski1, Cynthia Maxwell1, Rachel M Wald2, Jack M Colman2, Samuel C Siu3, Mathew Sermer1.   

Abstract

OBJECTIVES: Recommendations for the peripartum obstetric management of women with heart disease have included early induction of labour, shortening the second stage of labour during vaginal delivery, and low threshold for elective Caesarean section, although such techniques may result in complications. The objective of this study was to determine whether a less aggressive approach without routine preterm induction, shortening of the second stage, or Caesarean section adversely affects the mother or neonate.
METHODS: We examined peripartum obstetric management and its relationship with adverse maternal and neonatal outcomes in 1677 pregnancies: 559 in women with heart disease and 1118 in women without heart disease (control subjects). Logistic regression with propensity matching was used to compare outcomes in women with and without heart disease.
RESULTS: Women with heart disease were more likely than control subjects to undergo induction of labour (P < 0.001). Induction of labour tended to be at term and for logistical reasons, not for the indication of maternal heart disease. Assisted vaginal deliveries were more common in women with heart disease (29% vs. 11%, P < 0.001) than in those without, and the second stage of labour was also more prolonged in women with heart disease. Rates of Caesarean section were similar in both groups (P = 0.66). A significant proportion of women with heart disease had unassisted vaginal deliveries. Invasive cardiac monitoring was rarely used. Adverse maternal cardiac events at delivery were rare (2% of pregnancies) and were not associated with mode of delivery. In multivariate analysis, maternal heart disease was not predictive of adverse neonatal events or third- or fourth- degree lacerations. Maternal heart disease was associated with postpartum hemorrhage, but this was not related to assisted delivery or prolonged second stage of labour.
CONCLUSION: This large study has shown that in women with heart disease, avoidance of early induction of labour, rare use of Caesarean section for cardiac indications, and selective use of invasive monitoring produces safe obstetric outcomes.

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Year:  2012        PMID: 22971448     DOI: 10.1016/S1701-2163(16)35378-6

Source DB:  PubMed          Journal:  J Obstet Gynaecol Can        ISSN: 1701-2163


  4 in total

1.  Pregnancy in women with congenital heart disease.

Authors:  Rachael Hatton; Candice K Silversides
Journal:  Obstet Med       Date:  2013-12-01

Review 2.  Pregnancy in women with congenital heart disease.

Authors:  Rohan D'Souza; Mathew Sermer; Candice K Silversides
Journal:  Obstet Med       Date:  2015-02-27

3.  Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease.

Authors:  Joris Hrycyk; Harald Kaemmerer; Nicole Nagdyman; Moritz Hamann; Ktm Schneider; Bettina Kuschel
Journal:  PLoS One       Date:  2016-12-22       Impact factor: 3.240

Review 4.  Adult Congenital Heart Disease with Pregnancy.

Authors:  Koichiro Niwa
Journal:  Korean Circ J       Date:  2018-04       Impact factor: 3.243

  4 in total

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