| Literature DB >> 22969311 |
Asma Hayati Ahmad1, Zalina Ismail.
Abstract
The discovery that c-fos, a proto-oncogene, has a role in pain, has triggered extensive research on the consequences of c-fos expression. It has been shown that c-fos, through its protein form, FOS, leads to expression of dynorphin gene and subsequently dynorphin protein which is implicated in the development of a pain state. This mini review looks at the properties of c-fos and the consequences of its expression following noxious (painful) stimulation.Entities:
Keywords: c-fos; dynorphin; pain
Year: 2002 PMID: 22969311 PMCID: PMC3436108
Source DB: PubMed Journal: Malays J Med Sci ISSN: 1394-195X