| Literature DB >> 2296851 |
C Faivre-Sarrailh1, C Ferraz, J P Liautard, A Rabié.
Abstract
The actin mRNA content of the cerebellum was determined in normal and hypothyroid developing rats using RNA dot hybridization with a beta-actin cDNA probe. The decline in actin mRNA content occurring during the second postnatal week in normal development was delayed by about 1 week in hypothyroid rats. Since this effect coincides exactly with the delay in actin filament formation recently reported in thyroid-deficient rats, it strengthens the hypothesis of an inverse relationship in the developing brain between the polymerization state of actin and the production of actin mRNA.Entities:
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Year: 1990 PMID： 2296851 DOI： 10.1016/0736-5748(90)90026-x
Source DB: PubMed Journal: Int J Dev Neurosci ISSN： 0736-5748 Impact factor: 2.457