BACKGROUND: The clinical presentation of cardiac abnormalities in HIV-infected patients may be atypical or masked by concurrent illnesses that lead to misdiagnosis or they remain undiagnosed; therefore, this study was aimed to determine the frequency of cardiac abnormalities in HIV-infected patients. MATERIAL AND METHODS: Consecutive HIV-infected patients of age >13 years were studied for 3 months, after obtaining their consent. After clinical assessment, chest x-ray, electrocardiogram, 2-dimensional echocardiography and serum Troponin T levels were done. RESULTS: A total of 100 patients were studied, cardiomegaly was observed in the x-ray of 15% of them, abnormal electrocardiogram was seen in 18%, 2-dimensional echocardiography was abnormal in 67%; and diastolic dysfunction (42.8%) was the commonest abnormality followed by dilated cardiomyopathy (17.6%). Serum troponin T was elevated in 8%. The variables, opportunistic infections (OIs), antiretroviral therapy (ART), stage of HIV disease, and CD4 counts, did not affect the frequency of diastolic dysfunction. CONCLUSION: The diastolic dysfunction is the most common cardiac abnormality observed in HIV-infected patients.
BACKGROUND: The clinical presentation of cardiac abnormalities in HIV-infectedpatients may be atypical or masked by concurrent illnesses that lead to misdiagnosis or they remain undiagnosed; therefore, this study was aimed to determine the frequency of cardiac abnormalities in HIV-infectedpatients. MATERIAL AND METHODS: Consecutive HIV-infectedpatients of age >13 years were studied for 3 months, after obtaining their consent. After clinical assessment, chest x-ray, electrocardiogram, 2-dimensional echocardiography and serum Troponin T levels were done. RESULTS: A total of 100 patients were studied, cardiomegaly was observed in the x-ray of 15% of them, abnormal electrocardiogram was seen in 18%, 2-dimensional echocardiography was abnormal in 67%; and diastolic dysfunction (42.8%) was the commonest abnormality followed by dilated cardiomyopathy (17.6%). Serum troponin T was elevated in 8%. The variables, opportunistic infections (OIs), antiretroviral therapy (ART), stage of HIV disease, and CD4 counts, did not affect the frequency of diastolic dysfunction. CONCLUSION: The diastolic dysfunction is the most common cardiac abnormality observed in HIV-infectedpatients.
Authors: Eric A Secemsky; Rebecca Scherzer; Elaine Nitta; Alan H B Wu; David C Lange; Steven G Deeks; Jeffrey N Martin; James Snider; Peter Ganz; Priscilla Y Hsue Journal: JACC Heart Fail Date: 2015-07-08 Impact factor: 12.035
Authors: Rimke Bijker; Jun Yong Choi; Rossana Ditangco; Sasisopin Kiertiburanakul; Man Po Lee; Sarawut Siwamogsatham; Sanjay Pujari; Jeremy Ross; Chi-Yuen Wong; Wing-Wai Wong; Evy Yunihastuti; Matthew Law Journal: Open AIDS J Date: 2017-08-21
Authors: Niels C Pedersen; Michel Perron; Michael Bannasch; Elizabeth Montgomery; Eisuke Murakami; Molly Liepnieks; Hongwei Liu Journal: J Feline Med Surg Date: 2019-02-13 Impact factor: 2.015