Literature DB >> 2296720

Prenylated proteins: the structure of the isoprenoid group.

H C Rilling1, E Breunger, W W Epstein, P F Crain.   

Abstract

The mevalonate-derived portion of a prenylated protein from Chinese hamster ovary cells has been established as diterpenoid (C20). This group is linked to a carboxyl-terminal cysteine as a thioether. It was removed from the protein by hydrazinolysis followed by Raney nickel desulfurization, and the resulting hydrocarbon fraction was analyzed by gas chromatography-mass spectrometry.

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Year:  1990        PMID： 2296720     DOI： 10.1126/science.2296720

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  34 in total

1.  Prenylation of mammalian Ras protein in Xenopus oocytes.

Authors:  R Kim; J Rine; S H Kim
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

2.  GGPPS, a new EGR-1 target gene, reactivates ERK 1/2 signaling through increasing Ras prenylation.

Authors:  Ning Shen; Yue Shao; Shan-Shan Lai; Long Qiao; Run-Lin Yang; Bin Xue; Fei-Yan Pan; Hua-Qun Chen; Chao-Jun Li
Journal:  Am J Pathol       Date:  2011-10-06       Impact factor: 4.307

3.  A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.

Authors:  K Yokoyama; G W Goodwin; F Ghomashchi; J A Glomset; M H Gelb
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-15       Impact factor: 11.205

4.  Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.

Authors:  A A Finegold; D I Johnson; C C Farnsworth; M H Gelb; S R Judd; J A Glomset; F Tamanoi
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

5.  Geranylgeranyl pyrophosphate synthase encoded by the newly isolated gene GGPS6 from Arabidopsis thaliana is localized in mitochondria.

Authors:  X F Zhu; K Suzuki; T Saito; K Okada; K Tanaka; T Nakagawa; H Matsuda; M Kawamukai
Journal:  Plant Mol Biol       Date:  1997-10       Impact factor: 4.076

6.  Isoprenoid modification of rab proteins terminating in CC or CXC motifs.

Authors:  R Khosravi-Far; R J Lutz; A D Cox; L Conroy; J R Bourne; M Sinensky; W E Balch; J E Buss; C J Der
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

7.  Quantitation of prenylcysteines by a selective cleavage reaction.

Authors:  W W Epstein; D Lever; L M Leining; E Bruenger; H C Rilling
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

8.  Characterization of a second highly conserved B-type lamin present in cells previously thought to contain only a single B-type lamin.

Authors:  T H Höger; K Zatloukal; I Waizenegger; G Krohne
Journal:  Chromosoma       Date:  1990-10       Impact factor: 4.316

9.  Cigarette smoke-induced pulmonary inflammatory responses are mediated by EGR-1/GGPPS/MAPK signaling.

Authors:  Ning Shen; Tao Gong; Jian-Dong Wang; Fan-Li Meng; Long Qiao; Run-Lin Yang; Bin Xue; Fei-Yan Pan; Xiao-Jun Zhou; Hua-Qun Chen; Wen Ning; Chao-Jun Li
Journal:  Am J Pathol       Date:  2010-12-23       Impact factor: 4.307

10.  Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acid.

Authors:  B T Kinsella; R A Erdman; W A Maltese
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205
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