Literature DB >> 22964570

Chapter 12 Epidemiology of Staphylococcus aureus bacteraemia amongst patients receiving dialysis for established renal failure in England in 2009 to 2011: a joint report from the Health Protection Agency and the UK Renal Registry.

Lisa Crowley1, Jennie Wilson, Rebecca Guy, David Pitcher, Richard Fluck.   

Abstract

INTRODUCTION: Infection remains one of the leading causes of death in patients with end-stage renal failure (ESRF) receiving dialysis. Since April 2007, all centres providing renal replacement therapy in England have been required to provide additional data on patients with Methicillin Resistant Staphylococcus Aureus (MRSA) infection. From January 2011 this has also been required for patients with Methicillin Sensitive Staphylococcus Aureus (MSSA). MRSA data for 2009-2011 and the first 6 months of MSSA data are reported.
METHODS: Potential bacteraemia were identified by the Health Protection Agency based on clinical details provided and the clinical setting. The records were 'shared' with the parent renal centre who then complete the additional data on the HCAI-DCS website. Centres were also contacted by phone and email as a further validation step.
RESULTS: From April 2009-2010 there were 77 confirmed episodes of MRSA bacteraemia at a median rate of 0.25 per 100 prevalent dialysis patients. This number decreased to 61 episodes between April 2010-2011 at a median rate of 0 per 100 prevalent dialysis patients. Overall there has been an 82% reduction in absolute episodes since the first year of mandatory reporting in 2007. The incidence of bacteraemia in patients with a central venous catheter was approximately six fold higher than in those with an AV fistula. From 1st January to 30th June 2011 there were 160 episodes of MSSA bacteraemia with a rate of 1.06 episodes per 100 dialysis patients, again the risk was six fold higher in patients with a CVC.
CONCLUSIONS: Overall rates of MRSA bacteraemia in dialysis patients continued to fall although there remained variation between renal centres. Initial data from the early days of MSSA reporting suggested high rates of infection and an even greater variation between renal centres. This requires confirmation from future data collection.
Copyright © 2012 S. Karger AG, Basel.

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Year:  2012        PMID: 22964570     DOI: 10.1159/000342856

Source DB:  PubMed          Journal:  Nephron Clin Pract        ISSN: 1660-2110


  5 in total

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Authors:  S McNicholas; A Fe Talento; J O'Gorman; M M Hannan; M Lynch; C M Greene; P J Conlon; A C Shore; D C Coleman; H Humphreys; D Fitzgerald-Hughes
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2016-09-09       Impact factor: 3.267

2.  The characteristics and outcome of bacteraemia in renal transplant recipients and non-transplant renal patients.

Authors:  Mark Melzer; Territa Santhakumaran; Catherine Welch
Journal:  Infection       Date:  2016-05-02       Impact factor: 3.553

3.  Efficacy profile of a bivalent Staphylococcus aureus glycoconjugated vaccine in adults on hemodialysis: Phase III randomized study.

Authors:  Ali Fattom; Albert Matalon; John Buerkert; Kimberly Taylor; Silvia Damaso; Dominique Boutriau
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

4.  Development and Validation of a Clinical Prediction Rule for Bacteremia among Maintenance Hemodialysis Patients in Outpatient Settings.

Authors:  Sho Sasaki; Takeshi Hasegawa; Hiroo Kawarazaki; Atsushi Nomura; Daisuke Uchida; Takahiro Imaizumi; Masahide Furusho; Hiroki Nishiwaki; Shingo Fukuma; Yugo Shibagaki; Shunichi Fukuhara
Journal:  PLoS One       Date:  2017-01-12       Impact factor: 3.240

5.  Association of Kidney Function with Infections by Multidrug-Resistant Organisms: An Electronic Medical Record Analysis.

Authors:  Guobin Su; Hong Xu; Emilia Riggi; Zhiren He; Liming Lu; Bengt Lindholm; Gaetano Marrone; Zehuai Wen; Xusheng Liu; David W Johnson; Juan-Jesus Carrero; Cecilia Stålsby Lundborg
Journal:  Sci Rep       Date:  2018-09-06       Impact factor: 4.379

  5 in total

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