Literature DB >> 22963521

Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids.

Aya Kakizaki1, Taku Fujimura, Masato Mizuashi, Akiko Watabe, Yumi Kambayashi, Setsuya Aiba.   

Abstract

We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.
© 2012 The Authors Australasian Journal of Dermatology © 2012 The Australasian College of Dermatologists.

Entities:  

Keywords:  CD8+MF; hypohidrosis; syringotropism; vorinostat

Mesh：

Substances：

Year:  2012        PMID： 22963521     DOI： 10.1111/j.1440-0960.2012.00944.x

Source DB:  PubMed          Journal:  Australas J Dermatol        ISSN： 0004-8380            Impact factor:   2.875


  3 in total

1.  Syringotropic Mycosis Fungoides: A Rare Form of Cutaneous T-cell Lymphoma Enabling a Histopathologic "Sigh of Relief".

Authors:  Larisa M Lehmer; Kyle T Amber; Sébastien M de Feraudy
Journal:  Am J Dermatopathol       Date:  2017-12       Impact factor: 1.533

2.  Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease.

Authors:  Sadanori Furudate; Taku Fujimura; Yumi Kambayashi; Setsuya Aiba
Journal:  Case Rep Dermatol       Date:  2013-04-05

3.  Profiles of tumor-infiltrating lymphocytes in a case of trichilemmal carcinoma with spontaneous regression.

Authors:  Sadanori Furudate; Taku Fujimura; Akira Tsukada; Yukikazu Numata; Yumi Kambayashi; Setsuya Aiba
Journal:  Case Rep Dermatol       Date:  2012-10-16
  3 in total

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