Literature DB >> 22961905

Serine-type carboxypeptidase KexA of Aspergillus oryzae has broader substrate specificity than Saccharomyces cerevisiae Kex1 and is required for normal hyphal growth and conidiation.

Hiroto Morita1, Sayako Tomita, Hiroshi Maeda, Ayako Okamoto, Youhei Yamagata, Ken-Ichi Kusumoto, Hitoshi Amano, Hiroki Ishida, Michio Takeuchi.   

Abstract

Aspergillus oryzae has an ortholog of Saccharomyces cerevisiae KEX1, termed kexA. A truncated form of KexA protein showed serine-type carboxypeptidase activity and somewhat broader substrate specificity than Kex1 protease. Furthermore, our results indicated that KexA is required for normal growth of A. oryzae and that it might be involved in hyphal branching.

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Year:  2012        PMID： 22961905      PMCID： PMC3485961          DOI： 10.1128/AEM.01601-12

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  16 in total

Review 1.  K1 killer toxin, a pore-forming protein from yeast.

Authors:  H Bussey
Journal:  Mol Microbiol       Date:  1991-10       Impact factor: 3.501

2.  Alpha-factor leader-directed secretion of heterologous proteins from yeast.

Authors:  A J Brake
Journal:  Methods Enzymol       Date:  1990       Impact factor: 1.600

3.  Structure of a yeast pheromone gene (MF alpha): a putative alpha-factor precursor contains four tandem copies of mature alpha-factor.

Authors:  J Kurjan; I Herskowitz
Journal:  Cell       Date:  1982-10       Impact factor: 41.582

4.  Purification and characterization of a new type of acid carboxypeptidase from Aspergillus.

Authors:  E Ichishima
Journal:  Biochim Biophys Acta       Date:  1972-01-20

5.  Characterization of the yeast KEX1 gene product: a carboxypeptidase involved in processing secreted precursor proteins.

Authors:  A Cooper; H Bussey
Journal:  Mol Cell Biol       Date:  1989-06       Impact factor: 4.272

6.  Hormone (pheromone) processing enzymes in yeast. The carboxy-terminal processing enzyme of the mating pheromone alpha-factor, carboxypeptidase ysc alpha, is absent in alpha-factor maturation-defective kex1 mutant cells.

Authors:  J C Wagner; D H Wolf
Journal:  FEBS Lett       Date:  1987-09-14       Impact factor: 4.124

7.  Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and alpha-factor precursor processing.

Authors:  A Dmochowska; D Dignard; D Henning; D Y Thomas; H Bussey
Journal:  Cell       Date:  1987-08-14       Impact factor: 41.582

8.  Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging.

Authors:  Peter Hauptmann; Ludwig Lehle
Journal:  J Biol Chem       Date:  2008-05-12       Impact factor: 5.157

9.  brlA is necessary and sufficient to direct conidiophore development in Aspergillus nidulans.

Authors:  T H Adams; M T Boylan; W E Timberlake
Journal:  Cell       Date:  1988-07-29       Impact factor: 41.582

10.  The Golgi-resident protease Kex2 acts in conjunction with Prm1 to facilitate cell fusion during yeast mating.

Authors:  Maxwell G Heiman; Alex Engel; Peter Walter
Journal:  J Cell Biol       Date:  2007-01-08       Impact factor: 10.539
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  3 in total

1.  Proteomics of Fusarium oxysporum race 1 and race 4 reveals enzymes involved in carbohydrate metabolism and ion transport that might play important roles in banana Fusarium wilt.

Authors:  Yong Sun; Xiaoping Yi; Ming Peng; Huicai Zeng; Dan Wang; Bo Li; Zheng Tong; Lili Chang; Xiang Jin; Xuchu Wang
Journal:  PLoS One       Date:  2014-12-02       Impact factor: 3.240

2.  Dipeptidase PEPDA Is Required for the Conidiation Pattern Shift in Metarhizium acridum.

Authors:  Juan Li; Xueling Su; Yueqing Cao; Yuxian Xia
Journal:  Appl Environ Microbiol       Date:  2021-09-10       Impact factor: 4.792

3.  Transcriptional analysis of the conidiation pattern shift of the entomopathogenic fungus Metarhizium acridum in response to different nutrients.

Authors:  Zhenglong Wang; Kai Jin; Yuxian Xia
Journal:  BMC Genomics       Date:  2016-08-09       Impact factor: 3.969
  3 in total

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