Literature DB >> 22961450

Derivative scores from site accessibility and ranking of miRNA target predictions.

Abu Z M Dayem Ullah1, Sudhakar Sahoo, Kathleen Steinhöfel, Andreas A Albrecht.   

Abstract

In the present study, we define derivative scoring functions from PITA and STarMir predictions. The scoring functions are evaluated for up to five selected miRNAs with a relatively large number of validated targets reported by TarBase and miRecords. The average ranking of validated targets returned by PITA and STarMir is compared to the average ranking produced by the new derivatives scores. We obtain an average improvement of 13.6% (STD∼5.7%) relative to the average ranking of validated targets produced by PITA and STarMir.

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Year:  2012        PMID: 22961450     DOI: 10.1504/IJBRA.2012.048966

Source DB:  PubMed          Journal:  Int J Bioinform Res Appl        ISSN: 1744-5485


  2 in total

1.  Increased BCAR1 predicts poor outcomes of non-small cell lung cancer in multiple-center patients.

Authors:  Bo Deng; Zhifu Sun; Wampfler Jason; Ping Yang
Journal:  Ann Surg Oncol       Date:  2013-08-01       Impact factor: 5.344

2.  The genetic variants in 3' untranslated region of voltage-gated sodium channel alpha 1 subunit gene affect the mRNA-microRNA interactions and associate with epilepsy.

Authors:  Tian Li; Yaoyun Kuang; Bin Li
Journal:  BMC Genet       Date:  2016-07-29       Impact factor: 2.797

  2 in total

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