Literature DB >> 22961066

Can chronic multimorbidity explain the age-related differences in strength, speed and balance in older adults?

Anna-Karin Welmer1, Ingemar Kåreholt, Sara Angleman, Elisabeth Rydwik, Laura Fratiglioni.   

Abstract

BACKGROUND AND AIMS: It is known that physical performance declines with age in general, however there remains much to be understood in terms of age-related differences amongst older adults across a variety of physical components (such as speed, strength and balance), and particularly in terms of the role played by multimorbidity of chronic diseases. We aimed to detect the age-related differences across four components of physical performance and to explore to what extent chronic diseases and multimorbidity may explain such differences.
METHODS: We analyzed cross-sectional data from a population-based sample of 3323 people, aged 60 years and older from the SNAC-K study, Stockholm, Sweden. Physical performance was assessed by trained nurses using several tests (grip strength, walking speed, balance and chair stands). Clinical diagnoses were made by the examining physician based on clinical history and examination.
RESULTS: Censored normal regression analyses showed that the 72-90+ year-old persons had 17-40% worse grip strength, 44-86% worse balance, 30-86% worse chair stand score, and 21-59% worse walking speed, compared with the 60-66 year-old persons. Chronic diseases were strongly associated with physical impairment, and this association was particularly strong among the younger men. However, chronic diseases explained only some of the age-related differences in physical performance. When controlling for chronic diseases in the analyses, the age-related differences in physical performance changed 1-11%.
CONCLUSION: In spite of the strong association between multimorbidity and physical impairment, chronic morbidities explained only a small part of the age-related differences in physical performance.

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Year:  2012        PMID: 22961066     DOI: 10.3275/8584

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


  11 in total

Review 1.  Multimorbidity and functional impairment-bidirectional interplay, synergistic effects and common pathways.

Authors:  A Calderón-Larrañaga; D L Vetrano; L Ferrucci; S W Mercer; A Marengoni; G Onder; M Eriksdotter; L Fratiglioni
Journal:  J Intern Med       Date:  2018-11-22       Impact factor: 8.989

Review 2.  Aging and Multimorbidity: New Tasks, Priorities, and Frontiers for Integrated Gerontological and Clinical Research.

Authors:  Elisa Fabbri; Marco Zoli; Marta Gonzalez-Freire; Marcel E Salive; Stephanie A Studenski; Luigi Ferrucci
Journal:  J Am Med Dir Assoc       Date:  2015-05-07       Impact factor: 4.669

3.  Influencing factors for the decline of limb muscle strength and the association with all-cause mortality: evidence from a nationwide population-based cohort study.

Authors:  Jiaxiang Gao; Yudian Qiu; Yunfei Hou; Liyi Zhang; Kai Wang; Zhaoyu Chen; Qian Liu; Jianhao Lin
Journal:  Aging Clin Exp Res       Date:  2021-07-27       Impact factor: 3.636

4.  Age-related variation in health status after age 60.

Authors:  Giola Santoni; Sara Angleman; Anna-Karin Welmer; Francesca Mangialasche; Alessandra Marengoni; Laura Fratiglioni
Journal:  PLoS One       Date:  2015-03-03       Impact factor: 3.240

5.  Subtypes of physical frailty: Latent class analysis and associations with clinical characteristics and outcomes.

Authors:  Li-Kuo Liu; Chao-Yu Guo; Wei-Ju Lee; Liang-Yu Chen; An-Chun Hwang; Ming-Hsien Lin; Li-Ning Peng; Liang-Kung Chen; Kung-Yee Liang
Journal:  Sci Rep       Date:  2017-04-11       Impact factor: 4.379

6.  Trajectories of functional decline in older adults with neuropsychiatric and cardiovascular multimorbidity: A Swedish cohort study.

Authors:  Davide L Vetrano; Debora Rizzuto; Amaia Calderón-Larrañaga; Graziano Onder; Anna-Karin Welmer; Roberto Bernabei; Alessandra Marengoni; Laura Fratiglioni
Journal:  PLoS Med       Date:  2018-03-06       Impact factor: 11.069

7.  Geriatric Health Charts for Individual Assessment and Prediction of Care Needs: A Population-Based Prospective Study.

Authors:  Giola Santoni; Amaia Calderón-Larrañaga; Davide L Vetrano; Anna-Karin Welmer; Nicola Orsini; Laura Fratiglioni
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2020-01-01       Impact factor: 6.053

8.  Education-related differences in physical performance after age 60: a cross-sectional study assessing variation by age, gender and occupation.

Authors:  Anna-Karin Welmer; Ingemar Kåreholt; Elisabeth Rydwik; Sara Angleman; Hui-Xin Wang
Journal:  BMC Public Health       Date:  2013-07-10       Impact factor: 3.295

9.  Sex differences in associations between multimorbidity and physical function domains among community-dwelling adults in Singapore.

Authors:  Lixia Ge; Chun Wei Yap; Bee Hoon Heng
Journal:  PLoS One       Date:  2018-05-14       Impact factor: 3.240

10.  Associations Between Factors Across Life and One-Legged Balance Performance in Mid and Later Life: Evidence From a British Birth Cohort Study.

Authors:  Joanna M Blodgett; Rachel Cooper; Daniel H J Davis; Diana Kuh; Rebecca Hardy
Journal:  Front Sports Act Living       Date:  2020-04-07
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