Frank Fetterolf1, Michael Marceau. 1. Department of Clinical Sciences, The Commonwealth Medical College, Scranton, PA 17701, USA. Electronic address: ffetterolf@tcmedc.org.
Abstract
OBJECTIVE: Stuttering is a frequent side effect of many psychotropic drugs, particularly antidepressants. METHOD: This is a case report of a woman presenting with stuttering after starting bupropion treatment for her depression. RESULTS: The patient's stuttering resolved after discontinuing the bupropion. CONCLUSION: Neuroimaging and pharmacological studies have implicated dopamine in the pathophysiology of stuttering. Bupropion's ability to increase dopamine in the frontal cortex was suspected to have been involved in this patient's stuttering. However, further research is needed before causality can be assured.
OBJECTIVE: Stuttering is a frequent side effect of many psychotropic drugs, particularly antidepressants. METHOD: This is a case report of a woman presenting with stuttering after starting bupropion treatment for her depression. RESULTS: The patient's stuttering resolved after discontinuing the bupropion. CONCLUSION: Neuroimaging and pharmacological studies have implicated dopamine in the pathophysiology of stuttering. Bupropion's ability to increase dopamine in the frontal cortex was suspected to have been involved in this patient's stuttering. However, further research is needed before causality can be assured.