OBJECTIVE: To explore the relationships between body mass index and overall, physical, and psychosocial health-related quality of life (HRQoL) in children and adolescents. STUDY DESIGN: A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Medline, Embase, PsycINFO, and the Web of Knowledge were searched for relevant articles. Inclusion was restricted to participants under 20 years of age, assessed using the Pediatric Quality of Life Inventory. Random-effects meta-analysis, meta-regression, and cumulative meta-analysis were conducted. Heterogeneity was assessed using the I(2) statistic, and potential publication and small study bias were evaluated using funnel plots and the Egger test. RESULTS: Eleven eligible studies provided 35 estimates of effect size, derived from a total of 13210 study participants. Based on self-reports, children and adolescents with above-normal body mass index had significantly lower total, physical, and psychosocial HRQoL, with a clear dose relationship across all categories. In obese children and adolescents, the overall score was reduced by 10.6 points (95% CI, 14.0-7.2; P < .001). Parents reported the same pattern but a larger effect size. The total parental score for obese children and adolescents was reduced by 18.9 points (95% CI, 26.6-11.1; P < .001). No significant publication or small study bias was observed. CONCLUSION: Parents overestimate the impact of obesity on the HRQoL of their children. Nonetheless, obese children and adolescents have significantly reduced overall, physical, and psychosocial HRQoL.
OBJECTIVE: To explore the relationships between body mass index and overall, physical, and psychosocial health-related quality of life (HRQoL) in children and adolescents. STUDY DESIGN: A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Medline, Embase, PsycINFO, and the Web of Knowledge were searched for relevant articles. Inclusion was restricted to participants under 20 years of age, assessed using the Pediatric Quality of Life Inventory. Random-effects meta-analysis, meta-regression, and cumulative meta-analysis were conducted. Heterogeneity was assessed using the I(2) statistic, and potential publication and small study bias were evaluated using funnel plots and the Egger test. RESULTS: Eleven eligible studies provided 35 estimates of effect size, derived from a total of 13210 study participants. Based on self-reports, children and adolescents with above-normal body mass index had significantly lower total, physical, and psychosocial HRQoL, with a clear dose relationship across all categories. In obesechildren and adolescents, the overall score was reduced by 10.6 points (95% CI, 14.0-7.2; P < .001). Parents reported the same pattern but a larger effect size. The total parental score for obesechildren and adolescents was reduced by 18.9 points (95% CI, 26.6-11.1; P < .001). No significant publication or small study bias was observed. CONCLUSION: Parents overestimate the impact of obesity on the HRQoL of their children. Nonetheless, obesechildren and adolescents have significantly reduced overall, physical, and psychosocial HRQoL.
Authors: Julia K Kolodziejczyk; Kyle Gutzmer; Shana M Wright; Elva M Arredondo; Linda Hill; Kevin Patrick; Jeannie S Huang; Michael Gottschalk; Gregory J Norman Journal: Qual Life Res Date: 2014-07-01 Impact factor: 4.147
Authors: Kelly A M Ligthart; Winifred D Paulis; Dewi Djasmo; Bart W Koes; Marienke van Middelkoop Journal: Qual Life Res Date: 2014-12-05 Impact factor: 4.147
Authors: Amanda E Staiano; Robbie A Beyl; Daniel S Hsia; Amber R Jarrell; Peter T Katzmarzyk; Savarra Mantzor; Robert L Newton; Patrice Tyson Journal: Child Obes Date: 2017-04-25 Impact factor: 2.992
Authors: Neuza Silva; Marco Pereira; Christiane Otto; Ulrike Ravens-Sieberer; Maria Cristina Canavarro; Monika Bullinger Journal: Qual Life Res Date: 2019-05-04 Impact factor: 4.147