Literature DB >> 22958485

Signaling from the podocyte intercellular junction to the actin cytoskeleton.

Britta George1, Lawrence B Holzman.   

Abstract

Observations of hereditary glomerular disease support the contention that podocyte intercellular junction proteins are essential for junction formation and maintenance. Genetic deletion of most of these podocyte intercellular junction proteins results in foot process effacement and proteinuria. This review focuses on the current understanding of molecular mechanisms by which podocyte intercellular junction proteins such as the nephrin-neph1-podocin-receptor complex coordinate cytoskeletal dynamics and thus intercellular junction formation, maintenance, and injury-dependent remodeling.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22958485      PMCID： PMC3438455          DOI： 10.1016/j.semnephrol.2012.06.002

Source DB:  PubMed          Journal:  Semin Nephrol        ISSN： 0270-9295            Impact factor:   5.299


  126 in total

1.  Nck proteins maintain the adult glomerular filtration barrier.

Authors:  Nina Jones; Laura A New; Megan A Fortino; Vera Eremina; Julie Ruston; Ivan M Blasutig; Lamine Aoudjit; Youling Zou; Xiuwen Liu; Guo-Liang Yu; Tomoko Takano; Susan E Quaggin; Tony Pawson
Journal:  J Am Soc Nephrol       Date:  2009-05-14       Impact factor: 10.121

2.  Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome.

Authors:  Tobias B Huber; Björn Hartleben; Kirstin Winkelmann; Lisa Schneider; Jan U Becker; Michael Leitges; Gerd Walz; Hermann Haller; Mario Schiffer
Journal:  J Am Soc Nephrol       Date:  2009-03-11       Impact factor: 10.121

3.  Expression of galectin-1, a new component of slit diaphragm, is altered in minimal change nephrotic syndrome.

Authors:  Mariko Shimizu; Jamshid Khoshnoodi; Yoshihiro Akimoto; Hayato Kawakami; Hiroshi Hirano; Eiji Higashihara; Makoto Hosoyamada; Yuji Sekine; Ryota Kurayama; Hideaki Kurayama; Kensuke Joh; Jun Hirabayashi; Kenichi Kasai; Karl Tryggvason; Noriko Ito; Kunimasa Yan
Journal:  Lab Invest       Date:  2008-12-15       Impact factor: 5.662

4.  Slit diaphragms contain tight junction proteins.

Authors:  Hirotaka Fukasawa; Scott Bornheimer; Krystyna Kudlicka; Marilyn G Farquhar
Journal:  J Am Soc Nephrol       Date:  2009-05-28       Impact factor: 10.121

Review 5.  New insights into the role of podocytes in proteinuria.

Authors:  Jaakko Patrakka; Karl Tryggvason
Journal:  Nat Rev Nephrol       Date:  2009-07-07       Impact factor: 28.314

6.  Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia.

Authors:  Stephen J Warner; Gregory D Longmore
Journal:  J Cell Biol       Date:  2009-06-08       Impact factor: 10.539

7.  Cdc42 and Par proteins stabilize dynamic adherens junctions in the Drosophila neuroectoderm through regulation of apical endocytosis.

Authors:  Kathryn P Harris; Ulrich Tepass
Journal:  J Cell Biol       Date:  2008-12-08       Impact factor: 10.539

8.  Nephrin deficiency activates NF-kappaB and promotes glomerular injury.

Authors:  Sagair Hussain; Leile Romio; Moin Saleem; Peter Mathieson; Manuel Serrano; Jorge Moscat; Maria Diaz-Meco; Peter Scambler; Ania Koziell
Journal:  J Am Soc Nephrol       Date:  2009-06-04       Impact factor: 14.978

9.  An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.

Authors:  Tomonori Hirose; Daisuke Satoh; Hidetake Kurihara; Chiho Kusaka; Hiroko Hirose; Kazunori Akimoto; Taiji Matsusaka; Iekuni Ichikawa; Tetsuo Noda; Shigeo Ohno
Journal:  PLoS One       Date:  2009-01-14       Impact factor: 3.240

10.  CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney.

Authors:  Jenny Nyström; Kjell Hultenby; Sara Ek; Jonas Sjölund; Håkan Axelson; Karin Jirström; Moin A Saleem; Kristina Nilsson; Martin E Johansson
Journal:  Nephrol Dial Transplant       Date:  2009-01-21       Impact factor: 5.992
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  25 in total

1.  Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes.

Authors:  David Auguste; Mirela Maier; Cindy Baldwin; Lamine Aoudjit; Richard Robins; Indra R Gupta; Tomoko Takano
Journal:  Small GTPases       Date:  2016-01-04

Review 2.  The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.

Authors:  Florian Grahammer; Christoph Schell; Tobias B Huber
Journal:  Nat Rev Nephrol       Date:  2013-09-03       Impact factor: 28.314

3.  Nephrin Preserves Podocyte Viability and Glomerular Structure and Function in Adult Kidneys.

Authors:  Xuezhu Li; Peter Y Chuang; Vivette D D'Agati; Yan Dai; Rabi Yacoub; Jia Fu; Jin Xu; Oltjon Taku; Prem K Premsrirut; Lawrence B Holzman; John Cijiang He
Journal:  J Am Soc Nephrol       Date:  2015-02-02       Impact factor: 10.121

4.  Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier.

Authors:  Markus M Rinschen; Xiongwu Wu; Tim König; Trairak Pisitkun; Henning Hagmann; Caroline Pahmeyer; Tobias Lamkemeyer; Priyanka Kohli; Nicole Schnell; Bernhard Schermer; Stuart Dryer; Bernard R Brooks; Pedro Beltrao; Marcus Krueger; Paul T Brinkkoetter; Thomas Benzing
Journal:  J Am Soc Nephrol       Date:  2014-02-07       Impact factor: 10.121

5.  Disruption of the exocyst induces podocyte loss and dysfunction.

Authors:  Deepak Nihalani; Ashish K Solanki; Ehtesham Arif; Pankaj Srivastava; Bushra Rahman; Xiaofeng Zuo; Yujing Dang; Ben Fogelgren; Damian Fermin; Christopher E Gillies; Matthew G Sampson; Joshua H Lipschutz
Journal:  J Biol Chem       Date:  2019-05-09       Impact factor: 5.157

6.  Montelukast improves the changes of cytoskeletal and adaptor proteins of human podocytes by interleukin-13.

Authors:  Tae-Sun Ha; Ja Ae Nam; Su-Bin Seong; Moin A Saleem; Se Jin Park; Jae Il Shin
Journal:  Inflamm Res       Date:  2017-06-12       Impact factor: 4.575

7.  Nephrin Signaling Results in Integrin β1 Activation.

Authors:  Christopher Philipp Dlugos; Cara Picciotto; Carolin Lepa; Malte Krakow; Antje Stöber; Mee-Ling Eddy; Thomas Weide; Astrid Jeibmann; Michael P Krahn; Veerle Van Marck; Jürgen Klingauf; Andrea Ricker; Roland Wedlich-Söldner; Hermann Pavenstädt; Christian Klämbt; Britta George
Journal:  J Am Soc Nephrol       Date:  2019-05-16       Impact factor: 10.121

Review 8.  Semaphorin3a signaling, podocyte shape, and glomerular disease.

Authors:  Alda Tufro
Journal:  Pediatr Nephrol       Date:  2014-01-26       Impact factor: 3.714

Review 9.  The glomerulus: the sphere of influence.

Authors:  Martin R Pollak; Susan E Quaggin; Melanie P Hoenig; Lance D Dworkin
Journal:  Clin J Am Soc Nephrol       Date:  2014-05-29       Impact factor: 8.237

10.  Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes.

Authors:  J Bi; S E Chase; C D Pellenz; H Kurihara; A S Fanning; M Krendel
Journal:  Am J Physiol Renal Physiol       Date:  2013-06-12
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